Inhibition of gp130 alleviates LPS-induced lung injury by attenuating apoptosis and inflammation through JAK1/STAT3 signaling pathway

被引:0
|
作者
Fan Xu
Sijiao Wang
Yali Wang
Lijuan Hu
Lei Zhu
机构
[1] Zhongshan Hospital,Department of Pulmonary Medicine
[2] Fudan University,Department of Pulmonary and Critical Care Medicine
[3] Huadong Hospital Affiliated to Fudan University,undefined
来源
Inflammation Research | 2023年 / 72卷
关键词
Acute lung injury; Cell apoptosis; Inflammation; gp130; JAK1/STAT3;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:493 / 507
页数:14
相关论文
共 50 条
  • [1] Inhibition of gp130 alleviates LPS-induced lung injury by attenuating apoptosis and inflammation through JAK1/STAT3 signaling pathway
    Xu, Fan
    Wang, Sijiao
    Wang, Yali
    Hu, Lijuan
    Zhu, Lei
    INFLAMMATION RESEARCH, 2023, 72 (03) : 493 - 507
  • [2] Mutations leading to constitutive active gp130/JAK1/STAT3 pathway
    Pilati, Camilla
    Zucman-Rossi, Jessica
    CYTOKINE & GROWTH FACTOR REVIEWS, 2015, 26 (05) : 499 - 506
  • [3] Graveoline attenuates D-GalN/LPS-induced acute liver injury via inhibition of JAK1/STAT3 signaling pathway
    He, Jia
    Feng, Xu
    Liu, Yanyang
    Wang, Yuxin
    Ge, Chengyu
    Liu, Shao
    Jiang, Yueping
    BIOMEDICINE & PHARMACOTHERAPY, 2024, 177
  • [4] Protective Effect of Zuojin Fang on Lung Injury Induced by Sepsis through Downregulating the JAK1/STAT3 Signaling Pathway
    Yin, Jiangning
    Yu, Zhan
    Hou, Chuanyong
    Peng, Yigen
    Xiao, Jianpeng
    Jiang, Jun
    BIOMED RESEARCH INTERNATIONAL, 2021, 2021
  • [5] Gp130 Promotes Inflammation via the STAT3/JAK2 Pathway in Allergic Conjunctivitis
    Bao, Jiayu
    Zhang, Peng
    Wu, Binge
    Wang, Jingyi
    Li, Siyuan
    Li, Ao
    Jie, Ying
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2023, 64 (04)
  • [6] Calycosin Alleviates Oxidative Injury in Spinal Astrocytes by Regulating the GP130/JAK/STAT Pathway
    Song, Yingjun
    Li, Xu
    Liu, Xiaozhou
    Yu, Zhaozhong
    Zhang, Guofu
    JOURNAL OF OLEO SCIENCE, 2022, 71 (06) : 881 - 887
  • [7] The gp130/Jak/Stat3 pathway is required for Wnt induced regeneration and tumorigenesis in the mouse intestine
    Buchert, M.
    Phesse, T. J.
    Stuart, E. C.
    Ernst, M.
    EUROPEAN JOURNAL OF CANCER, 2013, 49 : S496 - S496
  • [8] gp130/Jak/Stat3 inhibition blocks WNT signaling-mediated intestinal tumorigenesis and regeneration
    Ernst, Matthias
    CANCER RESEARCH, 2014, 74 (19)
  • [9] AKR1C1 alleviates LPS-induced ALI in mice by activating the JAK2/STAT3 signaling pathway
    Wang, Xianjun
    Yang, Baocheng
    Li, Yuyu
    Luo, Jiye
    Wang, Yanli
    MOLECULAR MEDICINE REPORTS, 2021, 24 (06)
  • [10] Modulation of the IL-6-Signaling Pathway in Liver Cells by miRNAs Targeting gp 130, JAK1, and/or STAT3
    Servais, Florence A.
    Kirchmeyer, Melanie
    Hamdorf, Matthias
    Minoungou, Nadege W. E.
    Rose-John, Stefan
    Kreis, Stephanie
    Haan, Claude
    Behrmann, Iris
    MOLECULAR THERAPY-NUCLEIC ACIDS, 2019, 16 : 419 - 433