Extracellular Vesicles: the Next Frontier in Pregnancy Research

被引：0

作者：

Ali Afzal

Madeeha Khan

Zaman Gul

Rameen Asif

Sara Shahzaman

Asia Parveen

Muhammad Imran

Muhammad Babar Khawar

机构：

[1] University of Central Punjab,Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Science and Technology

[2] College of Allied Health Sciences,Department of Zoology

[3] Akhtar Saeed Medical and Dental College,Center for Applied Molecular Biology

[4] Institute of Zoology,Applied Molecular Biology & Biomedicine Lab, Department of Zoology

[5] University of the Punjab,undefined

[6] Government College University,undefined

[7] University of the Punjab,undefined

[8] Institute of Translational Medicine,undefined

[9] Medical College,undefined

[10] Yangzhou University,undefined

[11] University of Narowal,undefined

来源：

Reproductive Sciences | 2024年 / 31卷

关键词：

Extracellular vesicles; Pregnancy; Preeclampsia; Gestational diabetes mellitus; Preterm labor;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Extracellular vehicles (EVs) have been involved in several aspects of pregnancy, including endometrial receptivity, embryo implantation, and embryo-maternal communication showing them associated with pregnancy disorders, such as preeclampsia, gestational diabetes mellitus, and preterm birth. Further research is warranted to fully comprehend the exact pathophysiological roles of EVs and to develop new therapies targeting EVs thereby improving pregnancy outcomes. Herein, we review the recent knowledge on the multifaceted roles of EVs during pregnancy and address the majority of the molecular interactions between EVs, maternal, and fetal cells with an emphasis on disorders of pregnancy under the influence of EVs. Moreover, we also discuss its applications in clinical trials followed by prospects.

引用

页码：1204 / 1214

页数：10

共 451 条

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