FOXP1 suppresses the endothelial NLRP3 inflammasome

被引:0
|
作者
Gregory B. Lim
机构
[1] Nature Reviews Cardiology,
来源
Nature Reviews Cardiology | 2019年 / 16卷
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摘要
The transcription factor FOXP1 downregulates activation of the endothelial NLRP3 inflammasome and suppresses vascular inflammation, protecting against atherosclerosis. Upregulation of FOXP1 expression is a novel anti-atherogenic effect of simvastatin.
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页码:578 / 579
页数:1
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