Translational development of ABCB5+ dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers

被引:0
作者
Andreas Kerstan
Kathrin Dieter
Elke Niebergall-Roth
Sabrina Klingele
Michael Jünger
Christoph Hasslacher
Georg Daeschlein
Lutz Stemler
Ulrich Meyer-Pannwitt
Kristin Schubert
Gerhard Klausmann
Titus Raab
Matthias Goebeler
Korinna Kraft
Jasmina Esterlechner
Hannes M. Schröder
Samar Sadeghi
Seda Ballikaya
Martin Gasser
Ana M. Waaga-Gasser
George F. Murphy
Dennis P. Orgill
Natasha Y. Frank
Christoph Ganss
Karin Scharffetter-Kochanek
Markus H. Frank
Mark A. Kluth
机构
[1] University Hospital Würzburg,Department of Dermatology, Venereology and Allergology
[2] RHEACELL GmbH & Co. KG,Department of Dermatology
[3] TICEBA GmbH,Department of Clinical Research and Development
[4] University Hospital Greifswald,Department of Surgery
[5] Clinical Study Center St. Josefskrankenhaus,Division of Renal (Kidney) Medicine, Brigham and Women’s Hospital
[6] Diabetologikum DDG Ludwigshafen,Department of Dermatology, Brigham and Women’s Hospital
[7] MARE Clinic,Division of Plastic Surgery, Brigham and Women’s Hospital
[8] medamed GmbH,Department of Medicine
[9] Studienzentrum Aschaffenburg,Division of Genetics, Brigham and Women’s Hospital
[10] Diabetologikum Raab,Transplant Research Program
[11] University Hospital Würzburg,Harvard Stem Cell Institute
[12] Harvard Medical School,Department of Dermatology and Allergic Diseases
[13] Harvard Medical School,School of Medical and Health Sciences
[14] Harvard Medical School,Clinic of Dermatology, Immunology and Allergology
[15] VA Boston Healthcare System,undefined
[16] Harvard Medical School,undefined
[17] Boston Children’s Hospital,undefined
[18] Harvard Medical School,undefined
[19] Harvard University,undefined
[20] University Hospital,undefined
[21] Edith Cowan University,undefined
[22] Medical University Brandenburg “Theodor Fontane” Medical Center Dessau,undefined
来源
Stem Cell Research & Therapy | / 13卷
关键词
ABCB5; Advanced-therapy medicinal product; Angiogenesis; Chronic wound; Diabetic foot ulcer; Mesenchymal stem cells; Wound healing;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 537 条
  • [21] Barclay JI(2018)Identifying and treating foot ulcers in patients with diabetes: saving feet, legs and lives J Wound Care 27 S1-2587
  • [22] Chammas NK(2020)Practical Guidelines on the prevention and management of diabetic foot disease (IWGDF 2019 update) Diabetes Metab Res Rev 36 1419-1114
  • [23] Hill RL(2020)Effectiveness of interventions to enhance healing of chronic foot ulcers in diabetes: a systematic review Diabetes Metab Res Rev 36 1072-1447
  • [24] Edmonds ME(2017)Diabetes and wound angiogenesis Int J Mol Sci 18 889-645
  • [25] Dietrich I(2021)Diabetic wound-healing science Medicina 57 179-19431
  • [26] Braga GA(2022)The immune-centric revolution in the diabetic foot: monocytes and lymphocytes role in wound healing and tissue regeneration-a narrative review J Clin Med 11 245-3232
  • [27] de Melo FG(2016)Disturbed hypoxic responses as a pathogenic mechanism of diabetic foot ulcers Diabetes Metab Res Rev 32 256-13510
  • [28] da Costa Silva Silva ACC(2000)Large and sustained induction of chemokines during impaired wound healing in the genetically diabetic mouse: prolonged persistence of neutrophils and macrophages during the late phase of repair J Invest Dermatol 115 2579-217
  • [29] Martins-Mendes D(2011)Dysregulation of monocyte/macrophage phenotype in wounds of diabetic mice Cytokine 56 1103-291
  • [30] Monteiro-Soares M(2013)Blocking interleukin-1β induces a healing-associated wound macrophage phenotype and improves healing in type 2 diabetes Diabetes 62 1434-570