Learning in rats predisposed to catatonic states in a Morris water maze

被引:0
|
作者
Barykina N.N. [1 ]
Chugui V.F. [1 ]
Alekhina T.A. [1 ]
Ryazanova M.A. [2 ]
Ukolova T.N. [2 ]
Sakharov D.G. [1 ]
Kolpakov V.G. [1 ]
机构
[1] Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk
[2] Department of Biochemistry, Altai State University, Barnaul
基金
俄罗斯基础研究基金会;
关键词
catalepsy; catatonia; GC rats; Morris maze; pendulum-like movements; spatial learning;
D O I
10.1007/s11055-011-9417-6
中图分类号
学科分类号
摘要
Studies in a Morris water maze showed that GC rats, which are predisposed to catalepsy, did not differ from Wistar rats in terms of the proportion of correct attempts or the time taken to find a platform hidden beneath the water. However, in contrast to Wistar rats, rats of the cataleptic strain tended to show passive drifting and demonstrated longer-lasting episodes of immobility in the water. PLM+ rats, which are predisposed to hyperkinesia in the form of pendulum-like horizontal movements of the head and shoulder girdle, took longer to find the platform and showed a reduced proportion of correct platform-finding attempts than Wistar rats and PLM- rats, bred for the absence of pendulum-like movements. © 2011 Springer Science+Business Media, Inc.
引用
收藏
页码:309 / 315
页数:6
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