Overexpression of SIRT1 in vascular smooth muscle cells attenuates angiotensin II-induced vascular remodeling and hypertension in mice

[1] Levy D(2009)Genome-wide association study of blood pressure and hypertension Nat Genet 41 677-687

[2] Ehret GB(2001)Vascular remodeling in hypertension: roles of apoptosis, inflammation, and fibrosis Hypertension 38 581-587

[3] Rice K(2003)The role of angiotensin II in regulating vascular structural and functional changes in hypertension Curr Hypertens Rep 5 155-164

[4] Verwoert GC(2008)Transcriptional targets of sirtuins in the coordination of mammalian physiology Curr Opin Cell Biol 20 303-309

[5] Launer LJ(2008)Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice Cardiovasc Res 80 191-199

[6] Dehghan A(2010)SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis Eur Heart J 31 2301-2309

[7] Glazer NL(2012)Vascular smooth muscle cell sirtuin 1 protects against DNA damage and inhibits atherosclerosis Circulation 127 386-396

[8] Morrison AC(2011)SIRT1 acts as a modulator of neointima formation following vascular injury in mice Circ Res 108 1180-1189

[9] Johnson AD(2011)SIRT1 inhibits angiotensin II-induced vascular smooth muscle cell hypertrophy Acta Biochim Biophys Sin (Shanghai) 43 103-109

[10] Aspelund T(2008)SIRT1, a longevity gene, downregulates angiotensin II type 1 receptor expression in vascular smooth muscle cells Arterioscler Thromb Vasc Biol 28 1263-1269

[1] Levy D(2009)Genome-wide association study of blood pressure and hypertension Nat Genet 41 677-687

[2] Ehret GB(2001)Vascular remodeling in hypertension: roles of apoptosis, inflammation, and fibrosis Hypertension 38 581-587

[3] Rice K(2003)The role of angiotensin II in regulating vascular structural and functional changes in hypertension Curr Hypertens Rep 5 155-164

[4] Verwoert GC(2008)Transcriptional targets of sirtuins in the coordination of mammalian physiology Curr Opin Cell Biol 20 303-309

[5] Launer LJ(2008)Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice Cardiovasc Res 80 191-199

[6] Dehghan A(2010)SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis Eur Heart J 31 2301-2309

[7] Glazer NL(2012)Vascular smooth muscle cell sirtuin 1 protects against DNA damage and inhibits atherosclerosis Circulation 127 386-396

[8] Morrison AC(2011)SIRT1 acts as a modulator of neointima formation following vascular injury in mice Circ Res 108 1180-1189

[9] Johnson AD(2011)SIRT1 inhibits angiotensin II-induced vascular smooth muscle cell hypertrophy Acta Biochim Biophys Sin (Shanghai) 43 103-109

[10] Aspelund T(2008)SIRT1, a longevity gene, downregulates angiotensin II type 1 receptor expression in vascular smooth muscle cells Arterioscler Thromb Vasc Biol 28 1263-1269