Transgenic fluorescent zebrafish lines that have revolutionized biomedical research

被引：0
作者：
Chong Pyo Choe
Seok-Yong Choi
Yun Kee
Min Jung Kim
Seok-Hyung Kim
Yoonsung Lee
Hae-Chul Park
Hyunju Ro
机构：
[1] Gyeongsang National University,Division of Life Science
[2] Gyeongsang National University,Division of Applied Life Science, Plant Molecular Biology and Biotechnology Research Center
[3] Chonnam National University Medical School,Department of Biomedical Sciences
[4] Kangwon National University,Division of Biomedical Convergence, College of Biomedical Science
[5] Sookmyung Women’s University,Department of Biological Sciences
[6] Jeju National University,Department of Marine Life Sciences and Fish Vaccine Research Center
[7] Institute for Basic Science (IBS),Center for Genomic Integrity
[8] Korea University,Department of Biomedical Sciences, College of Medicine
[9] Chungnam National University,Department of Biological Sciences, College of Bioscience and Biotechnology
来源：
Laboratory Animal Research | / 37卷
关键词：
Zebrafish; Transgenic; Fluorescent; Signal; Skeletal; Hematopoietic; Nervous; Urogenital; Digestive; Organelle;
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摘要：
Since its debut in the biomedical research fields in 1981, zebrafish have been used as a vertebrate model organism in more than 40,000 biomedical research studies. Especially useful are zebrafish lines expressing fluorescent proteins in a molecule, intracellular organelle, cell or tissue specific manner because they allow the visualization and tracking of molecules, intracellular organelles, cells or tissues of interest in real time and in vivo. In this review, we summarize representative transgenic fluorescent zebrafish lines that have revolutionized biomedical research on signal transduction, the craniofacial skeletal system, the hematopoietic system, the nervous system, the urogenital system, the digestive system and intracellular organelles.
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