A comprehensive review of phytoconstituents in liver cancer prevention and treatment: targeting insights into molecular signaling pathways

被引：5

作者：

Islam, Md. Rezaul ^{[1
]}

Rauf, Abdur ^{[2
]}

Alash, Shopnil ^{[1
]}

Fakir, Md Naeem Hossain ^{[1
]}

Thufa, Gazi Kaifeara ^{[1
]}

Sowa, Mahbuba Sharmin ^{[1
]}

Mukherjee, Dattatreya ^{[3
]}

Kumar, Harendra ^{[4
]}

Hussain, Md Sadique ^{[5
]}

Aljohani, Abdullah S. M. ^{[6
]}

Imran, Muhammad ^{[7
]}

Al Abdulmonem, Waleed ^{[8
]}

Thiruvengadam, Rekha ^{[9
]}

Thiruvengadam, Muthu ^{[10
]}

机构：

[1] Daffodil Int Univ, Fac Allied Hlth Sci, Dept Pharm, Daffodil Smart City,Ashulia,Savar, Dhaka 1216, Bangladesh

[2] Univ Swabi, Dept Chem, Khyber Pakhtunkhwa 23561, Pakistan

[3] Raiganj Govt Med Coll & Hosp, Raiganj 733134, West Bengal, India

[4] Dow Univ Hlth Sci, Mission Rd,New Labour Colony Nanakwara, Karachi 74200, Sindh, Pakistan

[5] Suresh Gyan Vihar Univ, Sch Pharm, Mahal Rd, Jaipur 302017, Rajasthan, India

[6] Qassim Univ, Coll Vet Med, Dept Med Biosci, Buraydah, Saudi Arabia

[7] King Khalid Univ, Fac Sci, Dept Chem, POB 9004, Abha 61413, Saudi Arabia

[8] Qassim Univ, Coll Med, Dept Pathol, Buraydah, Saudi Arabia

[9] Saveetha Inst Med & Tech Sci SIMATS, Saveetha Med Coll, Ctr Global Hlth Res, Chennai, Tamilnadu, India

[10] Konkuk Univ, Coll Sanghuh Life Sci, Dept Crop Sci, Seoul 05029, South Korea

来源：

MEDICAL ONCOLOGY | 2024年 / 41卷 / 06期

关键词：

Natural products; Chinese herbal medicines; Liver cancer; Metastasis; Anticancer; Treatment; HUMAN HEPATOCELLULAR-CARCINOMA; CELL-CYCLE ARREST; ATTENUATES OXIDATIVE STRESS; PHOSPHATASE 2A ACTIVATION; HEPATIC ARTERIAL INFUSION; HIPPOPHAE-RHAMNOIDES L; NF-KAPPA-B; IN-VITRO; BREAST-CANCER; TUMOR-GROWTH;

D O I：

10.1007/s12032-024-02333-5

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Primary liver cancer is a type of cancer that develops in the liver. Hepatocellular carcinoma is a primary liver cancer that usually affects adults. Liver cancer is a fatal global condition that affects millions of people worldwide. Despite advances in technology, the mortality rate remains alarming. There is growing interest in researching alternative medicines to prevent or reduce the effects of liver cancer. Recent studies have shown growing interest in herbal products, nutraceuticals, and Chinese medicines as potential treatments for liver cancer. These substances contain unique bioactive compounds with anticancer properties. The causes of liver cancer and potential treatments are discussed in this review. This study reviews natural compounds, such as curcumin, resveratrol, green tea catechins, grape seed extracts, vitamin D, and selenium. Preclinical and clinical studies have shown that these medications reduce the risk of liver cancer through their antiviral, anti-inflammatory, antioxidant, anti-angiogenic, and antimetastatic properties. This article discusses the therapeutic properties of natural products, nutraceuticals, and Chinese compounds for the prevention and treatment of liver cancer.

引用

页数：25

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