Iron-Dependent Synthesis of Hemolysins by Staphylococcus aureus

被引：0

作者：

V. V. Leonov

V. V. Kosterina

V. V. Varnitsina

T. Kh. Timokhina

N. A. Kurlovich

机构：

[1] Yugorsk State University,Department of Chemistry

[2] Tyumen’ State Medical Academy,Department of Microbiology

来源：

Bulletin of Experimental Biology and Medicine | 2012年 / 153卷

关键词：

iron; hemolytic activity; hemolysins;

D O I：

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学科分类号：

摘要：

We studied the effect of Fe2+ on hemolysin synthesis by Staphylococcus aureus. Hemolytic activity of staphylococci was shown to be iron-dependent. Addition of Fe2+ to the nutrient medium induced the synthesis of α-hemolysin by staphylococci. Increasing the concentration of Fe2+ was followed by an increase in hemolytic activity of staphylococci. Inducible synthesis of α-hemolysin probably serves as an important pathogenetic factor in the development of staphylococcal infection in patients with excessive iron accumulation in the body.

引用

页码：41 / 43

页数：2