Epidemiology of nosocomial infections in selected neonatal intensive care units in Colombia, South America

被引：20

作者：

Efird M.M. ^{[1
]}

Rojas M.A. ^{[1
,10
]}

Lozano J.M. ^{[2
]}

Bose C.L. ^{[1
]}

Rojas M.X. ^{[2
]}

Rondón M.A. ^{[2
]}

Ruiz G. ^{[2
]}

Piñeros J.G. ^{[3
]}

Rojas C. ^{[4
]}

Robayo G. ^{[5
]}

Hoyos A. ^{[6
]}

Gosendi M.E. ^{[7
]}

Cruz H. ^{[8
]}

Leon A. ^{[9
]}

机构：

[1] University of North Carolina, Chapel Hill, NC

[2] Javeriana University, Bogotá

[3] Fundación Santa De de Bogotá, Bogotá

[4] Centro Policlínico del Olaya, Bogotá

[5] Hospital Universitario Clínica San Rafael, Bogotá

[6] Clínica del Country, Bogotá

[7] Clínica San Pedro Claver, Bogotá

[8] Fundación Valle de Lilli, Cali

[9] Hospital Simon Bolivar, Bogotá

[10] Vanderbilt University, Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Nashville

来源：

Journal of Perinatology | 2005年 / 25卷 / 8期

关键词：

D O I：

10.1038/sj.jp.7211345

中图分类号：

学科分类号：

摘要：

Objective: The epidemiology of nosocomial infections (NI) in neonatal intensive care units in developing countries has been poorly studied. We conducted a prospective study in selected neonatal units in Colombia, SA, to describe the incidence rate, causative organisms, and interinstitutional differences. Study design: Data were collected prospectively from February 20 to August 30, 2001 from eight neonatal units. NI was defined as culture-proven infection diagnosed after 72 h of hospitalization, resulting in treatment with antibiotics for >3 days. Linear regression models were used to describe associations between institutional variables and NI rates. Results: A total of 1504 infants were hospitalized for more than 72 h, and therefore, at risk for NI. Of all, 127 infections were reported among 80 patients (5.3%). The incidence density rate was 6.2 per 1000 patient-days. Bloodstream infections accounted for 78% of NIs. Gram-negative organisms predominated over gram-positive organisms (55 vs 38%) and were prevalent in infants ≤2000 g (54%). The most common pathogens were Staphylococcus epidermis (26%) and Klebsiella pneumonia (12%). Conclusion: Gram-negative organisms predominate in Colombia among infants <2000 g. The emergence of gram-negative organisms and their associated risk factors requires further study. © 2005 Nature Publishing Group. All rights reserved.

引用

页码：531 / 536

页数：5

共 19 条

[1] Stewart A.L., Turcan D.M., Rawlings G., Reynolds E.O.R., Prognosis for infants weighing 1000 grams or less at birth, Arch. Dis. Child, 52, pp. 97-104, (1977)
[2] Gaynes R.P., Edwards J.R., Jarvis W.R., Culver D.H., Tolson J.S., Martone W.J., Nosocomial infections among neonates in high-risk nurseries in the United States, Pediatrics, 98, pp. 357-361, (1996)
[3] Stover B.H., Shulman S.T., Bratcher D.F., Brady M.T., Levine G.L., Jarvis W.R., Nosocomial infection rates in US children's hospitals' neonatal and pediatric intensive care units, Am. J. Infect. Control., 29, pp. 152-157, (2001)
[4] Sohn A.H., Garrett D.O., Sinkowitz-Cochran R.L., Et al., Prevalence of nosocomial infections in neonatal intensive care unit patients: Results from the first national point-prevalence survey, J. Pediatr., 139, pp. 821-822, (2001)
[5] Mahieu L.M., Buitenweg N., Beutels P., De Dooy J.J., Additional hospital stay and charges due to hospital-acquired infections in a neonatal intensive care unit, J. Hosp. Infect., 47, pp. 223-229, (2001)
[6] Stoll B.J., Hansen N., Fanaroff A.A., Et al., Late-onset sepsis in very low birth weight neonates: The experience of the NICHD, Pediatrics, 110, pp. 285-291, (2002)
[7] Beck-Sague C.M., Azimi P., Fonseca S.N., Et al., Bloodstream infections in neonatal intensive care unit patients: Results of a multicenter study, Pediatr. Infect. Dis. J., 13, pp. 1110-1116, (1994)
[8] Policy statement: Organizational principals to guide and define the child health care system and/or improve the health of children, Pediatrics, 114, pp. 1341-1347, (2004)
[9] Inpatient perinatal care services, Guidelines for Perinatal Care, pp. 17-54, (2002)
[10] Lemons J.A., Bauer C.R., Oh W., Et al., Very low birth weight outcomes of the national institute of child health and human development neonatal research network, January 1995 through December 1996, Pediatrics, (2003)

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