Evidence for Diminished Functional Expression of Intestinal Transporters in Caco-2 Cell Monolayers at High Passages

被引：0
|
作者：
Hongshi Yu
Thomas J. Cook
Patrick J. Sinko
机构：
[1] Rutgers University,College of Pharmacy
[2] NaviCyte,undefined
[3] Inc.,undefined
来源：
Pharmaceutical Research | 1997年 / 14卷
关键词：
aqueous boundary layer; brush border enzymes; carrier-mediated transport; diffusion chamber; heterogeneity; permeability;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. To investigate the effects of passaging on the intrinsic membrane transport parameters of compounds absorbed by means of passive and carrier-mediated processes in the Caco-2 cell line.
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页码：757 / 762
页数：5
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