Management of acute basilar artery occlusion

被引：9
作者：
Schulte-Altedorneburg G. [1 ,2 ,3 ]
Mayer T.E. [2 ]
机构：
[1] Klinik für Diagnostische und Interventionelle Neuroradiologie, Universitätskliniken des Saarlandes, Homburg/Saar
[2] Abteilung für Neuroradiologie, Klinikum Großhadern, Ludwig-Maximilians-Universität München, München
[3] Klinik für Diagnostische und Interventionelle Neuroradiologie, Universitätskliniken des Saarlandes
来源：
Der Radiologe | 2007年 / 47卷 / 4期
关键词：
Basilar artery occlusion; Ischemic stroke; Mortality rate; Recanalization; Therapy standards;
D O I：
10.1007/s00117-007-1493-9
中图分类号：
学科分类号：
摘要：
Basilar artery thrombosis is a life-threatening condition whose unfavorable spontaneous prognosis can only be improved by early detection and subsequent aggressive recanalization therapy. The therapeutic approach has not yet been standardized and ranges from intravenous thrombolytic therapy with pharmacological agents to experimental procedures of mechanical endovascular recanalization, but the availability of the treatment approach and location of the occlusion determine the procedure in individual cases. Multicenter studies will have to clarify which bridging therapy (single administration of i.v. rt-PA or in combination with GPIIbIIIb inhibitors) before endovascular treatment is superior in terms of effectivity and complication rate. © 2007 Springer Medizin Verlag.
引用
收藏
页码：355 / 358
页数：3
相关论文
共 12 条
[1]  
Hacke W., Zeumer H., Ferbert A., Et al., Intra-arterial thrombolytic therapy improves outcome in patients with acute vertebrobasilar occlusive disease, Stroke, 19, pp. 1216-1222, (1988)
[2]  
Schulte-Altedorneburg G., Hamann G.F., Mull M., Et al., Outcome of acute vertebrobasilar occlusions treated with local intra-arterial fibrinolysis in 180 cases, AJNR, 27, pp. 2042-2047, (2006)
[3]  
Ferbert A., Bruckmann H., Drummen R., Clinical features of proven basilar artery occlusion, Stroke, 21, pp. 1135-1142, (1990)
[4]  
Pfefferkorn T., Mayer T.E., Schulte-Altedorneburg G., Et al., Diagnostik und Therapie der Basilaristhrombose, Nervenarzt, 77, pp. 416-422, (2006)
[5]  
Junghans U., Seitz R.J., Wittsack H.J., Et al., Treatment of acute basilar artery thrombosis with a combination of systemic alteplase and tirofiban, a nonpeptide platelet glycoprotein IIb/IIIa inhibitor: Report of four cases, Radiology, 221, pp. 795-801, (2001)
[6]  
Lindsberg P.J., Soinne L., Tatlisumak T., Et al., Long-term outcome after intravenous thrombolysis of basilar artery occlusion, JAMA, 292, pp. 1862-1866, (2004)
[7]  
Schulte-Altedorneburg G., Reith W., Bruckmann H., Et al., Thrombolysis of basilar artery occlusion - intra-arterial or intravenous: Is there really no difference?, Stroke, 38, (2007)
[8]  
Mayer T.E., Hamann G.F., Bruckmann H.J., Treatment of basilar artery embolism with a mechanical extraction device: Necessity of flow reversal, Stroke, 33, pp. 2232-2235, (2002)
[9]  
Mayer T.E., Hamann G.F., Schulte-Altedorneburg G., Bruckmann H., Treatment of vertebrobasilar occlusion by a coronary waterjet thrombectomy devicea pilot study, AJNR, 26, pp. 1389-1394, (2005)
[10]  
Schulte-Altedorneburg G., Bruckmann H., Hamann G.F., Et al., Ischemic and hemorrhagic complications following intra-arterial fibrinolysis in vertebrobasilar occlusion, AJNR, 28, pp. 378-381, (2007)
12