Associations of insulin resistance and type 2 diabetes to heart failure: Epidemiology, potential mechanisms, and clinical perspectives

被引：0

作者：

Ingelsson E. ^{[1
]}

机构：

[1] Department of Public Health and Caring Sciences, Uppsala University, SE-751 85 Uppsala, Uppsala Science Park

来源：

Current Cardiovascular Risk Reports | 2008年 / 2卷 / 1期

关键词：

Heart Failure; Insulin Resistance; Metformin; Chronic Heart Failure; Heart Failure Patient;

D O I：

10.1007/s12170-008-0012-5

中图分类号：

学科分类号：

摘要：

Heart failure, a common condition in most industrialized nations, is disabling and deadly. Type 2 diabetes, recognized as a risk factor for incident heart failure more than three decades ago, consistently has been associated with a twofold to threefold increased risk of heart failure and type 2 diabetes often coexist, and several studies have shown that type 2 diabetes in heart failure patients is associated with markedly increased mortality. Insulin resistance recently was reported to be a predictor of heart failure incidence independent of established risk factors, including diabetes and obesity. This review summarizes the literature regarding the associations of insulin resistance and type 2 diabetes to heart failure, and it discusses potential mechanisms underlying these associations and clinical perspectives. © 2008 Current Medicine Group LLC.

引用

页码：60 / 65

页数：5

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