Optical coherence tomography angiography findings of choroidal neovascularization in pseudoxanthoma elasticum

被引：10

作者：

Gal-Or O. ^{[1
,2
,5
]}

Balaratnasingam C. ^{[1
,2
,3
]}

Freund K.B. ^{[1
,2
,4
]}

机构：

[1] Manhattan Eye, Ear and Throat Hospital, LuEsther T. Mertz Retinal Research Center, New York, NY

[2] Vitreous-Retina-Macula Consultants of New York, 460 Park Avenue, 5th Floor, New York, 10022, NY

[3] University of Western Australia, Centre for Ophthalmology and Visual Sciences, Lions Eye Institute, Perth

[4] New York University School of Medicine, Department of Ophthalmology, New York, NY

[5] Rabin Medical Center, Ophthalmology Department, Petach Tikva

来源：

International Journal of Retina and Vitreous | / 1卷 / 1期

关键词：

Angioid streaks; Bruch's membrane; Choroidal neovasculariztion; Multimodal imaging; Optical coherence tomography angiography;

D O I：

10.1186/s40942-015-0011-x

中图分类号：

学科分类号：

摘要：

Angioid streaks (AS) are the most common ocular manifestation in patients with pseudoxanthoma elasticum (PXE). The major cause of severe visual loss in patients with AS is choroidal neovascularization (CNV). We report the optical coherence tomography angiography (OCTA) findings of CNV in a patient with PXE and angioid streaks. A 51-year-old man with PXE presented with visual disturbance in his right eye. Best corrected visual acuity was 20/30 OD and 20/30 OS. Funduscopic examination revealed angioid streaks and type 1 NV in his right eye. Multimodal imaging including OCTA demonstrated CNV nasal to the fovea. The morphology and configuration of CNV followed the path of the AS. OCTA combined with other multimodal imaging modalities may be a useful tool for diagnosing CNV secondary to angioid streaks in patients with pseudoxanthoma elasticum. The configuration of CNV in these may follow the path of angioid streaks implicating Bruch's membrane disruption as an important anatomical change in the pathogenesis of CNV. © 2015 Gal-Or et al.

引用

共 13 条

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