Bioactivities of major constituents isolated from Angelica sinensis (Danggui)

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作者
Wen-Wan Chao
Bi-Fong Lin
机构
[1] National Taiwan University,Department of Biochemical Science and Technology, College of Life Science
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关键词
Ferulic Acid; Unilateral Ureteral Obstruction; Murine Peritoneal Macrophage; Angelica Sinensis; Brain Tumor Cell Line;
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摘要
Danggui, also known as Angelica sinensis (Oliv.) Diels (Apiaceae), has been used in Chinese medicine to treat menstrual disorders. Over 70 compounds have been isolated and identified from Danggui. The main chemical constituents of Angelica roots include ferulic acid, Z-ligustilide, butylidenephthalide and various polysaccharides. Among these compounds, ferulic acid exhibits many bioactivities especially anti-inflammatory and immunostimulatory effects; Z-ligustilide exerts anti-inflammatory, anti-cancer, neuroprotective and anti-hepatotoxic effects; n-butylidenephthalide exerts anti-inflammatory, anti-cancer and anti-cardiovascular effects.
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