Prognostic impact of pretreatment T790M mutation on outcomes for patients with resected, EGFR-mutated, non-small cell lung cancer

被引：0
作者：
Yoshiya Matsumoto
Tomoya Kawaguchi
Masaru Watanabe
Shun-ichi Isa
Masahiko Ando
Akihiro Tamiya
Akihito Kubo
Chiyoe Kitagawa
Naoki Yoshimoto
Yasuhiro Koh
机构：
[1] Osaka Metropolitan University,Department of Respiratory Medicine, Graduate School of Medicine
[2] Internal Medicine III,Advanced Medicine and Clinical Research
[3] Wakayama Medical University,Division of Respiratory Medicine and Allergology, Department of Internal Medicine
[4] Clinical Research Center,Medical Oncology and Respiratory Medicine
[5] National Hospital Organization Kinki-chuo Chest Medical Center,Center for Biomedical Sciences, CIMS
[6] Nagoya University Hospital,undefined
[7] Internal Medicine,undefined
[8] National Hospital Organization Kinki-chuo Chest Medical Center,undefined
[9] Aichi Medical University School of Medicine,undefined
[10] Nagoya Medical Center,undefined
[11] Respiratory Medicine,undefined
[12] Ishikiriseiki Hospital,undefined
[13] Wakayama Medical University,undefined
来源：
BMC Cancer | / 22卷
关键词：
Non-small cell lung cancer; EGFR mutation; Pretreatment T790M; Resection; Recurrence-free survival;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 484 条
[1]  
Howlader N(2020)The effect of advances in lung-Cancer treatment on population mortality N Engl J Med 383 640-649
[2]  
Forjaz G(2013)Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers Clin Cancer Res 19 2240-2247
[3]  
Mooradian MJ(2016)Acquired resistance to first-line Afatinib and the challenges of prearranged progression biopsies J Thorac Oncol 11 2022-2026
[4]  
Meza R(2017)Osimertinib or platinum-Pemetrexed in EGFR T790M-positive lung Cancer N Engl J Med 376 629-640
[5]  
Kong CY(2018)Osimertinib in untreated EGFR-mutated advanced non-small-cell lung Cancer N Engl J Med 378 113-125
[6]  
Cronin KA(2007)Oncogenic activity of epidermal growth factor receptor kinase mutant alleles is enhanced by the T790M drug resistance mutation Cancer Res 67 7319-7326
[7]  
Mariotto AB(2006)Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer Cancer Res 66 7854-7858
[8]  
Lowy DR(2008)Detection of mutations in EGFR in circulating lung-cancer cells N Engl J Med 359 366-377
[9]  
Feuer EJ(2011)Pretreatment EGFR T790M mutation and BRCA1 mRNA expression in erlotinib-treated advanced non-small-cell lung cancer patients with EGFR mutations Clin Cancer Res 17 1160-1168
[10]  
Yu HA(2012)Pretreatment epidermal growth factor receptor (EGFR) T790M mutation predicts shorter EGFR tyrosine kinase inhibitor response duration in patients with non-small-cell lung cancer J Clin Oncol 30 433-440
12345678910