The histological variants of liposarcoma: predictive MRI findings with prognostic implications, management, follow-up, and differential diagnosis

被引：0
作者：
Magda Rizer
Adam D. Singer
Mark Edgar
Jean Jose
Ty K. Subhawong
机构：
[1] Mount Sinai Medical Center,Department of Radiology
[2] Emory Healthcare,Department of Radiology and Imaging Sciences, Section of Musculoskeletal Imaging
[3] Emory Healthcare,Bone and Soft Tissue Pathology, Department of Pathology
[4] Miller School of Medicine,Section of Musculoskeletal Imaging
[5] University of Miami,undefined
来源：
Skeletal Radiology | 2016年 / 45卷
关键词：
Liposarcoma; MRI; Management; Follow-up; Surveillance; Atypical lipomatous tumor;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Liposarcoma is the single most common soft tissue sarcoma accounting for up to 35 % of sarcomas. It represents a histologically diverse group of soft tissue tumors that demonstrate a wide range of imaging appearances with varied behavior patterns. Correspondingly, more aggressive histological subtypes often require management that includes a combination of surgery, chemotherapy, and radiation therapy. Distinguishing among liposarcoma subtypes has important therapeutic and prognostic implications. In this manuscript, we review the liposarcoma subtypes and their histologic and MRI findings, prognostic implications, and differential diagnostic considerations.
引用
收藏
页码：1193 / 1204
页数：11
相关论文
共 258 条
  • [1] Brennan MF(2014)Lessons learned from the study of 10,000 patients with soft tissue sarcoma Ann Surg 260 416-21
  • [2] Antonescu CR(2007)Myxoid/round cell and pleomorphic liposarcomas: prognostic factors and survival in a series of patients treated at a single institution Cancer 109 2522-31
  • [3] Moraco N(2005)From the archives of the AFIP: imaging of musculoskeletal liposarcoma with radiologic-pathologic correlation Radiographics 25 1371-95
  • [4] Singer S(2005)Differential sensitivity of liposarcoma subtypes to chemotherapy Eur J Cancer 41 2853-60
  • [5] Fiore M(2002)Imaging of fatty tumors: distinction of lipoma and well-differentiated liposarcoma Radiology 224 99-104
  • [6] Grosso F(1995)Malignant soft-tissue tumors in a large referral population: distribution of diagnoses by age, sex, and location AJR Am J Roentgenol 164 129-34
  • [7] Lo Vullo S(2013)MRI characteristics of lipoma and atypical lipomatous tumor/well-differentiated liposarcoma: retrospective comparison with histology and MDM2 gene amplification Skelet Radiol 42 635-47
  • [8] Pennacchioli E(2004)Lipomas, lipoma variants, and well-differentiated liposarcomas (atypical lipomas): results of MRI evaluations of 126 consecutive fatty masses AJR Am J Roentgenol 182 733-9
  • [9] Stacchiotti S(2013)Can experienced observers differentiate between lipoma and well-differentiated liposarcoma using only MRI? Sarcoma 2013 982784-85
  • [10] Ferrari A(2001)Pleomorphic liposarcoma Semin Diagn Pathol 18 274-61
12345678910