Development of microspheres for biomedical applications: A review

被引：166
作者：
Hossain K.M.Z. [1 ]
Patel U. [1 ]
Ahmed I. [1 ]
机构：
[1] Bioengineering and Advanced Materials Research Group, University of Nottingham, University Park, Nottingham
来源：
Progress in Biomaterials | 2015年 / 4卷 / 1期
基金：
英国科学技术设施理事会;
关键词：
Ceramics; Glasses; Microspheres; Polymers; Porous; Regenerative medicine; Tissue engineering;
D O I：
10.1007/s40204-014-0033-8
中图分类号：
学科分类号：
摘要：
An overview of microspheres manufactured for use in biomedical applications based on recent literature is presented in this review. Different types of glasses (i.e. silicate, borate, and phosphates), ceramics and polymerbased microspheres (both natural and synthetic) in the form of porous, non-porous and hollow structures that are either already in use or are currently being investigated within the biomedical area are discussed. The advantages of using microspheres in applications such as drug delivery, bone tissue engineering and regeneration, absorption and desorption of substances, kinetic release of the loaded drug components are also presented. This review also reports on the preparation and characterisation methodologies used for the manufacture of these microspheres. Finally, a brief summary of the existing challenges associated with processing these microspheres which requires further research and development are presented. © The Author(s) 2014.
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页码：1 / 19
页数：18
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