Structure of 2-acetoxy-3-(3-methoxy-4-acetoxy-5-chlorophenyl)-propenoic acid

被引：0

作者：

P. P. Haasbroek

D. W. Oliver

A. J. M. Carpy

机构：

[1] University of the Witwatersrand,Department of Pharmacy

[2] Potchefstroom University for C.H.E.,Department of Pharmacology

[3] Université de Bordeaux I,Laboratoire de Physico

来源：

Journal of Chemical Crystallography | 1998年 / 28卷

关键词：

X-ray; NMR; enol acetate; phenylpropenoic acid; azlactone;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

2-Acetoxy-3-(3-methoxy-4-acetoxy-5-chlorophenyl)-propenoic acid 2 was synthesized from the azlactone of 5-chlorovanillin and its structure confirmed by X-ray crystallography and nuclear magnetic resonance methods. Compound 2 crystallized with a molecule of acetic acid in the P-1(#2) space group (Z = 2) and with cell dimensions a = 6.303(2), b = 9.779(1), c = 15.528(3) Å, α = 101.46(2), β = 100.71(2) and γ = 90.21(2)°. This study reveals the formation of an α-acetoxy propenoic acid with a trans extended side acid side chain conformation. The 1H and 13C NMR spectral values of 2 also show the existence of the enolic ester in solution.

引用

页码：139 / 143

页数：4

共 18 条

[1]

Oliver D. W.(1994)undefined J. Chem. Crystallogr. 24 665-undefined

[2]

Haasbroek P. P.(1974)undefined Bull. Soc. Chim. Belg. 83 117-undefined

[3]

Leger J. M.(1930)undefined J. Am. Chem. Soc. 52 4576-undefined

[4]

Carpy A. J. M.(1943)undefined J. Org. Chem. 8 466-undefined

[5]

Anhoury M. L.(1987)undefined J. Chem. Soc. Perkin Trans. II S1-undefined

[6]

Crooy P.(undefined)undefined undefined undefined undefined-undefined

[7]

De Neys R.(undefined)undefined undefined undefined undefined-undefined

[8]

Eliaers J.(undefined)undefined undefined undefined undefined-undefined

[9]

Raiford L. C.(undefined)undefined undefined undefined undefined-undefined

[10]

Lichty J. G.(undefined)undefined undefined undefined undefined-undefined

← 1 2 →