Exploring the Clinical Utility of Metagenomic Next-Generation Sequencing in the Diagnosis of Pulmonary Infection

被引:0
作者
Guijuan Xie
Bo Zhao
Xun Wang
Liang Bao
Yiming Xu
Xian Ren
Jiali Ji
Ting He
Hongqing Zhao
机构
[1] The Affiliated Wuxi Second People’s Hospital of Nanjing Medical University,Department of Respiratory
[2] Affiliated Wuxi Clinical College of Nantong University,Department of Gastroenterology
[3] The Affiliated Wuxi Second People’s Hospital of Nanjing Medical University,undefined
来源
Infectious Diseases and Therapy | 2021年 / 10卷
关键词
Application; Bronchoalveolar lavage fluid (BALF); Bronchoscopy; Clinical diagnosis; Etiology; Metagenomic next-generation sequencing (mNGS); Mixed infection; Pulmonary infection; Transbronchial lung biopsy (TBLB);
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1419 / 1435
页数:16
相关论文
共 120 条
[1]  
Langelier C(2018)Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults Proc Natl Acad Sci USA 115 E12353-E12362
[2]  
Kalantar KL(2014)Multistate point-prevalence survey of health care-associated infections N Engl J Med 370 1198-1208
[3]  
Moazed F(2015)Making the leap from research laboratory to clinic: challenges and opportunities for next-generation sequencing in infectious disease diagnostics MBio 6 e01888-e1915
[4]  
Magill SS(2020)Diagnostic value of metagenomic next-generation sequencing for the detection of pathogens in bronchoalveolar lavage fluid in ventilator-associated pneumonia patients Front Microbiol 11 599756-371
[5]  
Edwards JR(2020)Blood and bronchoalveolar lavage fluid metagenomic next-generation sequencing in pneumonia Can J Infect Dis Med Microbiol 2020 6839103-1760
[6]  
Bamberg W(2016)Diagnosis of sepsis with cell-free DNA by next-generation sequencing technology in ICU patients Arch Med Res 47 365-s240
[7]  
Goldberg B(2014)The feasibility study of non-invasive fetal trisomy 18 and 21 detection with semiconductor sequencing platform PLoS ONE 9 e110240-3921
[8]  
Sichtig H(2009)Fast and accurate short read alignment with Burrows–Wheeler transform Bioinformatics 25 1754-169
[9]  
Geyer C(2018)Microbiological diagnostic performance of metagenomic next-generation sequencing when applied to clinical practice Clin Infect Dis 67 S231-578
[10]  
Ledeboer N(2014)Single-molecule long-read 16S sequencing to characterize the lung microbiome from mechanically ventilated patients with suspected pneumonia J Clin Microbiol 52 3913-449