Personalized genomic medicine

被引：0
作者：
Giuseppe Novelli
机构：
[1] Preside Facoltà Medicina e Chirurgia,
来源：
Internal and Emergency Medicine | 2010年 / 5卷
关键词：
Personalized medicine; Genomic medicine; Pharmacogenomics; Risk prediction;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Personalized medicine provide to physicians a molecular makeup of each patient. Looking at the patient on this level helps the physician get a profile of the patient’s genetic distinction, or mapping. By investigating this genetic profile, medical professionals are then able to select patients, and use the found information to plan out a course of treatment that is much more in step with the way their body works. Personalize medicine is a direct extension of the genomic medicine that use genetic information to prevent or treat disease in adults or their children.
引用
收藏
页码：81 / 90
页数：9
相关论文
共 428 条
  • [1] Kidd JM(2008)Mapping and sequencing of structural variation from eight human genomes Nature 453 56-64
  • [2] Cooper GM(2010)Genomic medicine—an updated primer N Engl J Med 362 2001-2011
  • [3] Donahue WF(2002)Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir Lancet 359 727-732
  • [4] Feero WG(2002)Genetic variations in HLA-B region and hypersensitivity reactions to abacavir Lancet 359 1121-1122
  • [5] Guttmacher AE(2004)Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant Proc Natl Acad Sci USA 101 4180-4185
  • [6] Collins FS(2004)Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations Pharmacogenomics 5 203-211
  • [7] Mallal S(2005)Clinical and immunogenetic correlates of abacavir hypersensitivity AIDS 19 979-981
  • [8] Nolan D(2008)PREDICT-1 study team. HLA-B*5701 screening for hypersensitivity to abacavir N Engl J Med 358 568-579
  • [9] Witt C(2002)The abacavir hypersensitivity reaction: a review Clin Ther 24 1502-1514
  • [10] Hetherington S(2004)Medical genetics: a marker for Stevens–Johnson syndrome Nature 428 486-1008
12345678910