Thromboembolic disease in COVID-19 patients: A brief narrative review

被引：0
作者：
Samhati Mondal
Ashley L. Quintili
Kunal Karamchandani
Somnath Bose
机构：
[1] University of Maryland School of Medicine,Department of Anesthesiology
[2] Penn State Health Milton S. Hershey Medical Center,Department of Pharmacy
[3] Penn State Health Milton S. Hershey Medical Center,Department of Anesthesiology and Perioperative Medicine
[4] Beth Israel Deaconess Medical Center,Department of Anesthesiology, Critical Care and Pain Medicine
[5] Harvard Medical School,undefined
来源：
Journal of Intensive Care | / 8卷
关键词：
COVID-19; thrombosis; thromboembolism; SARS-CoV2; management; coagulation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Corona virus 2 (SARS-CoV2/ Severe Acute Respiratory Syndrome Corona Virus 2) infection has emerged as a global health crisis. Incidence of thromboembolic disease is reported to be high in SARS-CoV2 disease and is seen in a multitude of organ systems ranging from cutaneous thrombosis to pulmonary embolism, stroke or coronary thrombosis sometimes with catastrophic outcomes. Evidence points towards a key role of thromboembolism, hypercoagulability and over production of proinflammatory cytokines mimicking a “cytokine storm” which leads to multiorgan failure. This brief narrative review highlights the pathophysiology and risk factors of thromboembolic disease and provides a framework for management of anticoagulation based on the current evidence.
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