Biological functions of MicroRNAs

被引:0
|
作者
Yong Huang
Xing Jia Shen
Quan Zou
Qiao Ling Zhao
机构
[1] Jiang Su University of Science and Technology,The Key Laboratory of Silkworm and Mulberry Genetic Improvement, Ministry of Agriculture, Sericultural Research Institute
[2] Chinese Academy of Agricultural Sciences,undefined
[3] School of Information Science and Technology of Xiamen University,undefined
关键词
microRNA; biogenesis; function; expression; diseases;
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中图分类号
学科分类号
摘要
The small regulatory non-coding RNA molecules, known as microRNAs (miRNAs), have been recognized as potential regulator of gene expression and modulate the gene function at the post-transcriptional level. It is now clear that miRNA biogenesis and function are related to the molecular mechanisms of various clinical diseases, which can potentially regulate every aspect of cellular activity, including differentiation and development, metabolism, proliferation, apoptotic cell death viral infection and tumorgenesis. Here, we review recent work and provide insight into the diverse roles of miRNAs.
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页码:684 / 689
页数:5
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