Characteristics of human saliva proteome and peptidome

被引：2
作者：
Kolesov S.A. [1 ]
Fedulova E.N. [1 ]
Lavrova A.E. [1 ]
机构：
[1] Volga Federal Medical Research Center, Nizhny Novgorod
来源：
Human Physiology | 2016年 / 42卷 / 4期
关键词：
diagnostics; peptidomics; proteins; proteomics; saliva;
D O I：
10.1134/S0362119716040058
中图分类号：
学科分类号：
摘要：
Recent studies on the characteristics of saliva proteome and peptidome greatly expanded our understanding of this biological fluid. Athough many scientists consider saliva to be an ideal biosubstrate in diagnosis of the human body state; currently, the research in this area is at the data accumulation stage. The physiology of saliva and salivary glands, as well as characteristics of interaction between the saliva proteins and the oral cavity microorganisms, has been insufficiently studied yet. The lack of standardization in collecting the saliva samples and in the proteome research protocols, and the requirements for sample representativeness introduce discrepancies in the results obtained by different researchers. Addressing these problems will allow the wide use of saliva proteome as a complex indicator of the functional state of the human body. © 2016, Pleiades Publishing, Inc.
引用
收藏
页码：463 / 468
页数：5
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