coBRIM: a phase 3, double-blind, placebo-controlled study of vemurafenib versus vemurafenib + cobimetinib in previously untreated BRAFV600 mutation–positive patients with unresectable locally advanced or metastatic melanoma (NCT01689519)

被引：8

作者：

Paolo A Ascierto

Grant A. McArthur

Brigitte Dréno

James Larkin

Gabriella Liszkay

Michele Maio

Mario Mandala

Lev Demidov

Daniil Stroyakovskiy

Luc Thomas

Luis de la Cruz-Merino

Victoria Atkinson

Caroline Dutriaux

Claus Garbe

Ilsung Chang

Stephen P. Hack

Antoni Ribas

机构：

[1] Istituto Nazionale Tumori Fondazione G. Pascale,

[2] Peter MacCallum Cancer Centre,undefined

[3] Hôtel Dieu Place Alexis Ricordeau,undefined

[4] The Royal Marsden Hospital,undefined

[5] National Institute of Oncology,undefined

[6] Azienda Ospedaliera Universitaria Senese,undefined

[7] Papa Giovanni XXIII Hospital,undefined

[8] N.N. Blokhin Russian Cancer Research Center,undefined

[9] Moscow City Oncology Hospital 62,undefined

[10] Centre Hospitalier Lyon Sud,undefined

[11] Hospital Universitario Virgen Macarena,undefined

[12] Princess Alexandra Hospital,undefined

[13] Hopital Saint André,undefined

[14] University of Tübingen,undefined

[15] Genentech,undefined

[16] Inc,undefined

[17] Jonsson Comprehensive Cancer Center at the University of California,undefined

[18] Los Angeles,undefined

来源：

Journal of Translational Medicine | / 13卷 / Suppl 1期

关键词：

Overall Survival; Metastatic Melanoma; Vemurafenib; Creatine Phosphokinase; BRAF Inhibitor;

D O I：

10.1186/1479-5876-13-S1-O4

中图分类号：

学科分类号：

摘要：

引用

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