First manifestation of psoriasis vulgaris in tumor necrosis factor receptor-associated periodic syndrome during treatment with etanercept [Erstmanifestation einer psoriasis vulgaris bei tumornekrosefaktor-rezeptor- 1-assoziiertem periodischem syndrom unter therapie mit etanercept]

被引：0

作者：

Boms S. ^{[1
,3
]}

Sehr T. ^{[1
]}

Jappe U. ^{[2
]}

Enk A. ^{[1
]}

机构：

[1] Paul-Ehrlich-Institut, Langen

[2] Universitäts-Hautklinik, Ruprecht-Karls Universität Heidelberg, 69115 Heidelberg

来源：

Der Hautarzt | 2008年 / 59卷 / 8期

关键词：

Etanercept; Hereditary periodic fever syndrome; Psoriasis; TRAPS; Tumour necrosis factor receptor;

D O I：

10.1007/s00105-007-1451-5

中图分类号：

学科分类号：

摘要：

Drugs antagonizing tumor necrosis factor (TNF) α have been increasingly and successfully used in the treatment of psoriasis vulgaris and psoriatic arthritis. We report a patient with TNF receptor 1-associated periodic syndrome (TRAPS) who received TNF-α antagonist etanercept. A month later, the patient developed for the first time generalized psoriasis vulgaris. This paradoxical phenomenon has been reported sporadically in patients receiving TNF-α antagonists for other inflammatory diseases. The cause of psoriasis induced by TNF-α antagonists is still obscure. © 2008 Springer Medizin Verlag.

引用

页码：653 / 655

页数：2