Corneal Histopathology in Stevens-Johnson Syndrome: A Case Report and Review of Literature

Stevens-Johnson syndrome is a life-threatening, immune-mediated, acute inflammatory disorder of the mucocutaneous membranes. It affects people of almost any age and has a high mortality and morbidity rate. Therefore, histopathological confirmation of the diagnosis is essential. Ocular involvement occurs in more than 50% of the affected patients. Here, we report a case of Stevens-Johnson syndrome with ocular involvement in a 10-year-old boy suffering from pain, burning, stinging, and decreased vision in both eyes for over 2 years. Histopathological findings were consistent with the changes due to the syndrome. Stevens-Johnson syndrome affects various mucous membranes along with the skin. Ocular involvement may manifest both acutely and chronically and causes morbidities. A careful clinical and histopathologic examination is required in order to give the correct diagnosis.