Visible Particle Identification Using Raman Spectroscopy and Machine Learning

[1] Jiskoot W(2012)Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release J Pharm Sci 101 946-954

[2] Randolph TW(2016)Mouse models for assessing protein immunogenicity: lessons and challenges J Pharm Sci 105 1567-1575

[3] Volkin DB(2014)Classification of glass particles in parenteral product vials by visual, microscopic, and spectroscopic methods PDA J Pharm Sci Technol 68 362-372

[4] Middaugh CR(2019)Indicative properties measurements by SEM, SEM-EDX and XRD for initial homogeneity tests of new certified reference materials Microchem J 146 429-433

[5] Schöneich C(2016)A systematic evaluation of mechanisms, material effects, and protein-dependent differences on friction-related protein particle formation in formulation and filling steps Int J Pharm 511 931-945

[6] Winter G(2010)Identification of an extraneous black particle in a glass syringe: extractables/leachables case study PDA J Pharm Sci Technol 64 242-248

[7] Jiskoot W(2019)The role of nanoanalytics in the development of organic-inorganic nanohybrids-seeing nanomaterials as they are Nanomaterials (Basel) 9 1673-830

[8] Kijanka G(2006)Molecular and elemental characterisation of mineral particles by means of parallel micro-Raman spectrometry and scanning electron microscopy/energy dispersive X-ray analysis Spectrochim Acta Part B At Spectrosc 61 824-834

[9] Randolph TW(2016)Quantitative aspects of inductively coupled plasma mass spectrometry Philos Trans A Math Phys Eng Sci 374 20150369-868

[10] Carpenter JF(2009)Raman microscopic applications in the biopharmaceutical industry: in situ identification of foreign particulates inside glass containers with aqueous formulated solutions Appl Spectrosc 63 830-3321

[1] Jiskoot W(2012)Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release J Pharm Sci 101 946-954

[2] Randolph TW(2016)Mouse models for assessing protein immunogenicity: lessons and challenges J Pharm Sci 105 1567-1575

[3] Volkin DB(2014)Classification of glass particles in parenteral product vials by visual, microscopic, and spectroscopic methods PDA J Pharm Sci Technol 68 362-372

[4] Middaugh CR(2019)Indicative properties measurements by SEM, SEM-EDX and XRD for initial homogeneity tests of new certified reference materials Microchem J 146 429-433

[5] Schöneich C(2016)A systematic evaluation of mechanisms, material effects, and protein-dependent differences on friction-related protein particle formation in formulation and filling steps Int J Pharm 511 931-945

[6] Winter G(2010)Identification of an extraneous black particle in a glass syringe: extractables/leachables case study PDA J Pharm Sci Technol 64 242-248

[7] Jiskoot W(2019)The role of nanoanalytics in the development of organic-inorganic nanohybrids-seeing nanomaterials as they are Nanomaterials (Basel) 9 1673-830

[8] Kijanka G(2006)Molecular and elemental characterisation of mineral particles by means of parallel micro-Raman spectrometry and scanning electron microscopy/energy dispersive X-ray analysis Spectrochim Acta Part B At Spectrosc 61 824-834

[9] Randolph TW(2016)Quantitative aspects of inductively coupled plasma mass spectrometry Philos Trans A Math Phys Eng Sci 374 20150369-868

[10] Carpenter JF(2009)Raman microscopic applications in the biopharmaceutical industry: in situ identification of foreign particulates inside glass containers with aqueous formulated solutions Appl Spectrosc 63 830-3321