The DNA damage response at eroded telomeres and tethering to the nuclear pore complex

被引：0
作者：
Basheer Khadaroo
M. Teresa Teixeira
Pierre Luciano
Nadine Eckert-Boulet
Susanne M. Germann
Marie Noelle Simon
Irene Gallina
Pauline Abdallah
Eric Gilson
Vincent Géli
Michael Lisby
机构：
[1] CNRS,Department of Biology
[2] Unité Propre de Recherche 3081,undefined
[3] Genome Instability and Carcinogenesis Conventionné par l'Université d'Aix-Marseille 2,undefined
[4] Laboratoire de Biologie Moléculaire de la Cellule,undefined
[5] UMR 5239,undefined
[6] CNRS/ ENS Lyon,undefined
[7] Université Lyon 1,undefined
[8] Ecole Normale Supérieure,undefined
[9] University of Copenhagen,undefined
来源：
Nature Cell Biology | 2009年 / 11卷
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学科分类号：
摘要：
Cells with a single short telomere and lacking telomerase mount a damage response consisting of recruitment of DNA damage checkpoint proteins, Cdc13, RPA and Rad52, many generations before senescence and in addition show tethering of the short telomere to the nuclear pore complex.
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页码：980 / 987
页数：7
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