The DNA damage response at eroded telomeres and tethering to the nuclear pore complex

被引：0
|
作者：
Basheer Khadaroo
M. Teresa Teixeira
Pierre Luciano
Nadine Eckert-Boulet
Susanne M. Germann
Marie Noelle Simon
Irene Gallina
Pauline Abdallah
Eric Gilson
Vincent Géli
Michael Lisby
机构：
[1] CNRS,Department of Biology
[2] Unité Propre de Recherche 3081,undefined
[3] Genome Instability and Carcinogenesis Conventionné par l'Université d'Aix-Marseille 2,undefined
[4] Laboratoire de Biologie Moléculaire de la Cellule,undefined
[5] UMR 5239,undefined
[6] CNRS/ ENS Lyon,undefined
[7] Université Lyon 1,undefined
[8] Ecole Normale Supérieure,undefined
[9] University of Copenhagen,undefined
来源：
Nature Cell Biology | 2009年 / 11卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Cells with a single short telomere and lacking telomerase mount a damage response consisting of recruitment of DNA damage checkpoint proteins, Cdc13, RPA and Rad52, many generations before senescence and in addition show tethering of the short telomere to the nuclear pore complex.
引用
收藏
页码：980 / 987
页数：7
相关论文
共 50 条
  • [1] The DNA damage response at eroded telomeres and tethering to the nuclear pore complex
    Khadaroo, Basheer
    Teixeira, M. Teresa
    Luciano, Pierre
    Eckert-Boulet, Nadine
    Germann, Susanne M.
    Simon, Marie Noelle
    Gallina, Irene
    Abdallah, Pauline
    Gilson, Eric
    Geli, Vincent
    Lisby, Michael
    NATURE CELL BIOLOGY, 2009, 11 (08) : 980 - U161
  • [2] DNA damage response to eroded telomeres
    Lisby, Michael
    Geli, Vincent
    CELL CYCLE, 2009, 8 (22) : 3617 - 3618
  • [3] NIPA located at the nuclear pore complex is involved in DNA damage response
    Kulinski, M.
    Schneider, K.
    von Klitzing, C.
    Leonhardt, H.
    Duyster, J.
    ONKOLOGIE, 2012, 35 : 79 - 79
  • [4] Complex interactions between the DNA-damage response and mammalian telomeres
    Arnoult, Nausica
    Karlseder, Jan
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2015, 22 (11) : 859 - 866
  • [5] Complex interactions between the DNA-damage response and mammalian telomeres
    Nausica Arnoult
    Jan Karlseder
    Nature Structural & Molecular Biology, 2015, 22 : 859 - 866
  • [6] SUMO-Dependent Relocalization of Eroded Telomeres to Nuclear Pore Complexes Controls Telomere Recombination
    Churikov, Dmitri
    Charifi, Ferose
    Eckert-Boulet, Nadine
    Silva, Sonia
    Simon, Marie-Noelle
    Lisby, Michael
    Geli, Vincent
    CELL REPORTS, 2016, 15 (06): : 1242 - 1253
  • [7] DNA damage response at functional and dysfunctional telomeres
    Longhese, Maria Pia
    GENES & DEVELOPMENT, 2008, 22 (02) : 125 - 140
  • [8] Telomeres, histone code, and DNA damage response
    Misri, S.
    Pandita, S.
    Kumar, R.
    Pandita, T. K.
    CYTOGENETIC AND GENOME RESEARCH, 2008, 122 (3-4) : 297 - 307
  • [9] DNA damage checkpoint adaptation genes are required for division of cells harbouring eroded telomeres
    Mersaoui, Sofiane Y.
    Gravel, Serge
    Karpov, Victor
    Wellinger, Raymund J.
    MICROBIAL CELL, 2015, 2 (10): : 394 - 405
  • [10] The fate of irreparable DNA double-strand breaks and eroded telomeres at the nuclear periphery
    Lisby, Michael
    Teixeira, Teresa
    Gilson, Eric
    Geli, Vincent
    NUCLEUS, 2010, 1 (02) : 158 - 161
12345