Neutralizing and enhancing antibodies against SARS-CoV-2

被引：0
作者：
Yafei Liu
Hisashi Arase
机构：
[1] Osaka University,Department of Immunochemistry, Research Institute for Microbial Diseases
[2] Osaka University,Laboratory of Immunochemistry, WPI Immunology Frontier Research Center
来源：
Inflammation and Regeneration | / 42卷
关键词：
SARS-CoV-2; Neutralizing antibody; Enhancing antibody;
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摘要：
The high transmissibility and rapid global spread of SARS-CoV-2 since 2019 has led to a huge burden on healthcare worldwide. Anti-SARS-CoV-2 neutralizing antibodies play an important role in not only protecting against infection but also in clearing the virus and are essential to providing long-term immunity. On the other hand, antibodies against the virus are not always protective. With the emergence of SARS-CoV-2 immune escape variants, vaccine design strategies as well as antibody-mediated therapeutic approaches have become more important. We review some of the findings on SARS-CoV-2 antibodies, focusing on both basic research and clinical applications.
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