Electrophysiological Effects of a Single Intravenous Administration of Ivabradine (S 16257) in Adult Patients with Normal Baseline Electrophysiology

被引：131
作者：
A. John Camm
Chu-Pak Lau
机构：
[1] St George’s Hospital,The Medical School
[2] Queen Mary Hospital,undefined
来源：
Drugs in R & D | 2003年 / 4卷 / 2期
关键词：
Catheter Ablation; Refractory Period; Ivabradine; Reduce Heart Rate; Radiofrequency Catheter Ablation;
D O I：
10.2165/00126839-200304020-00001
中图分类号：
学科分类号：
摘要：
Introduction: Ivabradine is a heart rate-lowering agent that selectively inhibits the pacemaker current, If, in the sinoatrial node. The objective of this study was to evaluate the effects of a single intravenous administration of ivabradine on cardiac electrophysiological parameters in patients with normal baseline electrophysiology. The safety profile of ivabradine was also investigated.
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页码：83 / 89
页数：6
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