Time to death predictors of HIV/AIDS infected patients on antiretroviral therapy in Ethiopia

被引:16
|
作者
Tadege M. [1 ]
机构
[1] Department of Statistics, Injibara University, Injibara Amhara
关键词
ART; HIV; Survival; TB;
D O I
10.1186/s13104-018-3863-y
中图分类号
学科分类号
摘要
Objective: The purpose of this study was to identify the major risk factors, which contributed to shortened survival time to death of HIV patients on antiretroviral therapy. Six-hundred HIV patients were included from two hospitals and six health centers record from January 2003 to December 2017. Kaplan-Meier and Cox proportional hazard model were implemented. Results: From the Kaplan-Meier, log-rank test result indicated that there was a significant difference between tuberculosis comorbidity (P =.000), occupation (P =.027), and WHO clinical stage (P =.012) on the survival experience of patients at 5% statistical significance level. From the Cox regression result, the risk of death for patients who lived with tuberculosis was about 2.872-fold times higher than those patients who were negative. Most of the HIV/AIDS patients on antiretroviral therapy were died in a short period due to tuberculosis comorbidity, began with lower amount of CD4, being underweight, merchant, and being on WHO clinical stage IV. © 2018 The Author(s).
引用
收藏
相关论文
共 50 条
  • [31] Nephrotoxicity associated with antiretroviral therapy in HIV-infected patients
    Harris, Marianne
    EXPERT OPINION ON DRUG SAFETY, 2008, 7 (04) : 389 - 400
  • [32] ANTIRETROVIRAL THERAPY AND ARTERIAL ELASTICITY IN HIV-INFECTED PATIENTS
    Kundro, Mariana A.
    Viloria, Guillermo A.
    Toibaro, Javier J.
    Losso, Marcelo H.
    MEDICINA-BUENOS AIRES, 2017, 77 (05) : 365 - 369
  • [33] Nephrotoxicity Associated with Antiretroviral Therapy in HIV-Infected Patients
    Rho, Mira
    Perazella, Mark A.
    CURRENT DRUG SAFETY, 2007, 2 (02) : 147 - 154
  • [34] Antiretroviral Therapy in HIV-Infected Infants and Children
    Maron, Gabriela
    Gaur, Aditya H.
    Flynn, Patricia M.
    PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2010, 29 (04) : 360 - 363
  • [35] Incidence of tuberculosis and early mortality in a large cohort of HIV infected patients receiving antiretroviral therapy in a tertiary hospital in Addis Ababa, Ethiopia
    Kassa, Aragie
    Teka, Azmera
    Shewaamare, Aster
    Jerene, Degu
    TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2012, 106 (06) : 363 - 370
  • [36] Barriers and outcomes: TB patients co-infected with HIV accessing antiretroviral therapy in rural Zambia
    Chileshe, Muatale
    Bond, Virginia Anne
    AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV, 2010, 22 : 51 - 59
  • [37] Ocular manifestation and their associated factors among HIV/AIDS patients receiving highly active antiretroviral therapy in Southern Ethiopia
    Amsalu, Anteneh
    Desta, Kindie
    Nigussie, Demiss
    Delelegne, Demoze
    INTERNATIONAL JOURNAL OF OPHTHALMOLOGY, 2017, 10 (05) : 776 - 781
  • [38] Predictors of Opportunistic Infections among HIV-infected Patients on Antiretroviral Therapy: A Cross-Sectional Study
    Gebru, Tsegu Hailu
    Mekonen, Haftea Hagos
    Kiros, Kbrom Gemechu
    Gebremedhin, Haftom Tesfay
    Teklemichael, Beyene Tadesse
    Tesfamichael, Yohannes Ashebir
    CLINICAL NURSING RESEARCH, 2023, 32 (07) : 1057 - 1065
  • [39] Predictors of early mortality in a cohort of HIV-infected children receiving high active antiretroviral treatment in public hospitals in Ethiopia
    Ebissa, Getachew
    Deyessa, Negusse
    Biadgilign, Sibhatu
    AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV, 2015, 27 (06): : 723 - 730
  • [40] Predictors of primary non-adherence to concomitant chronic treatment in HIV-infected patients with antiretroviral therapy
    Borrego, Yolanda
    Gomez-Fernandez, Encarnacion
    Jimenez, Rocio
    Cantudo, Rosa
    Almeida-Gonzalez, Carmen V.
    Morillo, Ramon
    EUROPEAN JOURNAL OF HOSPITAL PHARMACY, 2018, 25 (03) : 127 - 131