Peripheral arterial disease (PAD) assessed by ankle-brachial index in patients with established cardiovascular disease or at least one risk factor for atherosclerosis

被引:1
作者
Sharma S.K. [1 ]
Kohli A. [2 ]
Chopra E. [3 ]
机构
[1] Department of Cardiology, Super Specialty Hospital, Government Medical College, Jammu, 180001, Jammu
[2] Department of CTVS, Super Specialty Hospital, Government Medical College, Jammu, 180001, Jammu
[3] Department of Internal Medicine, Government Medical College, Jammu, 180001, Jammu
关键词
Ankle-brachial index; Cardiovascular disease; Peripheral arterial disease;
D O I
10.1007/s12055-015-0415-0
中图分类号
学科分类号
摘要
Background: Peripheral arterial disease is associated with high cardiovascular morbidity and mortality. The objective of this study was to identify unrecognized patients with peripheral arterial disease using ankle-brachial index in patients with established cardiovascular disease or at least one risk factor for atherosclerosis. Material and methods: One hundred fifty-four patients with 94 males and 60 females underwent assessment of peripheral arterial disease using ankle-brachial index by pulse Doppler. Correlation between peripheral arterial disease and various variables (history of cardiovascular disease or various risk factors for atherosclerosis) was established using Pearson coefficient correlation test and linear-by-linear association. Results: Peripheral arterial disease was present in 24.03 % (n = 37) of patients in the study population. A total of 22.08 % (n = 34) patients in study population had ankle-brachial index between 0.41 and 0.90, i.e., mild to moderate peripheral arterial disease, and 1.95 % (n = 3) had ankle-brachial index between 0.00 and 0.40, indicating severe peripheral arterial disease. Advancing age (p < 0.001; linear-by-linear association = 24.448), smoking (p < 0.001), diabetes (p = 0.005), hypertension (p = 0.008), hyperlipidemia (p < 0.001), cardiovascular disease (p = 0.003), and number of risk factors (p < 0.001; linear-by-linear association = 50.099) showed a statistically significant correlation with peripheral arterial disease. No significant difference was found between men and women (59.46 vs. 40.54 %, respectively, p = 0.051) in terms of peripheral arterial disease. Conclusion: Peripheral arterial disease is highly prevalent in patients with established cardiovascular disease or who have at least one risk factor for atherosclerosis. Screening of patients for peripheral arterial disease by pulse Doppler (which is cheap, rapid, and precise method to detect peripheral arterial disease) would allow identification of high-risk patients who could benefit from an appropriate treatment strategy. © 2016, Indian Association of Cardiovascular-Thoracic Surgeons.
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页码:120 / 125
页数:5
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共 28 条
  • [1] Selvin E., Erlinger T.P., Prevalence of and risk factors for peripheral arterial disease in the United States: results from the National Health and Nutrition Examination Survey, 1999–2000, Circulation, 110, pp. 738-743, (2004)
  • [2] J Vasc Surg, 44, pp. 333-338, (2006)
  • [3] Ramos R., Quesada M., Solanas P., Prevalence of symptomatic and asymptomatic peripheral arterial disease and the value of the ankle-brachial index to stratify cardiovascular risk, Eur J Vasc Endovasc Surg, 38, 3, pp. 305-311, (2009)
  • [4] Hirsch A.T., Haskal Z.J., Hertzer N.R., Et al., ACC/AHA 2005 Practice guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic), Circulation, 113, pp. e463-e654, (2006)
  • [5] Norgren L., Hiatt W.R., Dormandy J.A., Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II), Eur J Vasc Endovasc Surg, 33, pp. S1-S75, (2007)
  • [6] Aquino R., Johnnides C., Makaroun M., Natural history of claudication: long-term serial follow-up study of 1244 claudicants, J Vasc Surg, 34, pp. 962-970, (2001)
  • [7] Mostaza J.M., Gonzalez-Juanatey J.R., Castillo J., Et al., Prevalence of carotid stenosis and silent myocardial ischemia in asymptomatic subjects with a low ankle-brachial index, J Vasc Surg, 49, 1, pp. 104-108, (2009)
  • [8] Greenlandams J., Aurigemma G.P., Bond M.G., Et al., Prevention conference V. Beyond secondary prevention: identifying the high-risk patients for primary prevention. Noninvasive tests of atherosclerosis burden, Circulation, 101, pp. 1-7, (2000)
  • [9] Belch J.J., Topol E.J., Agnelli J., Et al., For the prevention of atherothrombotic disease network: critical issues in peripheral arterial disease in detection and management, Arch Intern Med, 163, 8, pp. 884-892, (2003)
  • [10] Hirsch A.T., Haskal Z.J., Hertzer N.R., ACC/AHA 2005 guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric and abdominal aortic): executive summary, J Am Coll Cardiol, 47, pp. e1-e192, (2006)