Effects of a botulinum toxin type A injection on the masseter muscle: An animal model study

被引:8
|
作者
Park S.-Y. [1 ]
Park Y.-W. [1 ]
Ji Y.-J. [2 ]
Park S.-W. [3 ]
Kim S.-G. [1 ,4 ]
机构
[1] Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University, Gangneung
[2] Department of Biomedical Engineering, Ulsan University, Ulsan
[3] Department of Electronic Engineering, Gangneung-Wonju National University, Gangneung
[4] Oral and Maxillofacial Surgery, Gangneung-Wonju National University-College of Dentistry, Gangneung
关键词
Botulinum toxin type A; Electromyography; Masseter muscle; Peak voltage;
D O I
10.1186/s40902-015-0010-8
中图分类号
学科分类号
摘要
Background: The aim of this study was to investigate the effect of a botulinum toxin type A (BTX-A) injection in the masseter muscle using electromyography (EMG) in an animal model. Methods: Ten male adult (>3 months of age) New Zealand white rabbits were used. Muscle activity was continuously recorded from 8 hours before to 8 hours after BTX-A injection. The rabbits received unilateral BTX-A injections of either 5 units (group 1, n = 5) or 20 units (group 2, n = 5). Results: The masseter muscle activity of the rabbits was significantly reduced immediately after BTX-A injection (P < 0.05 for both groups). When the results from group 1 were compared with those from group 2, only the peak voltage was significantly decreased in group 2 (P = 0.013). Conclusion: Masseter muscle activity measured by EMG was immediately decreased after a BTX-A injection. © 2015, Park et al.; licensee Springer.
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