Genome-wide association study identifies five susceptibility loci for glioma

被引:0
作者
Sanjay Shete
Fay J Hosking
Lindsay B Robertson
Sara E Dobbins
Marc Sanson
Beatrice Malmer
Matthias Simon
Yannick Marie
Blandine Boisselier
Jean-Yves Delattre
Khe Hoang-Xuan
Soufiane El Hallani
Ahmed Idbaih
Diana Zelenika
Ulrika Andersson
Roger Henriksson
A Tommy Bergenheim
Maria Feychting
Stefan Lönn
Anders Ahlbom
Johannes Schramm
Michael Linnebank
Kari Hemminki
Rajiv Kumar
Sarah J Hepworth
Amy Price
Georgina Armstrong
Yanhong Liu
Xiangjun Gu
Robert Yu
Ching Lau
Minouk Schoemaker
Kenneth Muir
Anthony Swerdlow
Mark Lathrop
Melissa Bondy
Richard S Houlston
机构
[1] The University of Texas M.D. Anderson Cancer Center,Department of Epidemiology
[2] Section of Cancer Genetics,Department of Radiation Sciences
[3] Institute of Cancer Research,Department of Clinical Neuroscience
[4] Service de Neurologie Mazarin and UMR 975 INSERM-UPMC,Department of Medical Epidemiology and Biostatistics
[5] GH Pitié-Salpêtrière,Department of Neurology
[6] APHP,Division of Molecular Genetic Epidemiology
[7] Oncology,Division of Epidemiology and Public Health
[8] Umeå University,undefined
[9] Neurochirurgische Universitätsklinik,undefined
[10] Centre National de Génotypage,undefined
[11] IG/CEA,undefined
[12] Umeå University,undefined
[13] Institute of Environmental Medicine,undefined
[14] Karolinska Institutet,undefined
[15] Karolinska Institutet,undefined
[16] University Hospital Zurich,undefined
[17] German Cancer Research Center (DKFZ),undefined
[18] Im Neuenheimer Feld 580,undefined
[19] Centre for Epidemiology and Biostatistics,undefined
[20] Faculty of Medicine and Health,undefined
[21] University of Leeds,undefined
[22] Texas Children's Cancer Center,undefined
[23] Baylor College of Medicine,undefined
[24] Section of Epidemiology,undefined
[25] Institute of Cancer Research,undefined
[26] University of Nottingham Medical School,undefined
[27] Queen's Medical Centre,undefined
[28] Foundation Jean Dausett-CEPH,undefined
来源
Nature Genetics | 2009年 / 41卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Richard Houlston, Melissa Bondy and colleagues identify variants at five loci associated with glioma susceptibility, providing insights into the etiology of this primary brain tumor. The risk loci include common variants near TERT, CDKN2A-CDKN2B and RTEL1.
引用
收藏
页码:899 / 904
页数:5
相关论文
共 55 条
[1]  
Bondy ML(2008)Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium Cancer 113 1953-1968
[2]  
Hemminki K(2003)Familial risks in nervous system tumors Cancer Epidemiol. Biomarkers Prev. 12 1137-1142
[3]  
Li X(2007)The INTERPHONE study: design, epidemiological methods, and description of the study population Eur. J. Epidemiol. 22 647-664
[4]  
Cardis E(2006)Cohort profile: 1958 British birth cohort (National Child Development Study) Int. J. Epidemiol. 35 34-41
[5]  
Power C(2007)A genome-wide association study identifies alleles in Nat. Genet. 39 870-874
[6]  
Elliott J(2007) associated with risk of sporadic postmenopausal breast cancer Nat. Genet. 39 645-649
[7]  
Hunter DJ(2005)Genome-wide association study of prostate cancer identifies a second risk locus at 8q24 Nat. Genet. 37 1243-1246
[8]  
Yeager M(2006)Population structure, differential bias and genomic control in a large-scale, case-control association study Oncogene 25 3735-3744
[9]  
Clayton DG(2008)Co-resistance to retinoic acid and TRAIL by insertion mutagenesis into RAM Biochim. Biophys. Acta 1783 1055-1067
[10]  
Yin W(2007)Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells Neurochem. Res. 32 2167-2183