Epigenetic Regulation of Organic Anion Transporting Polypeptide 1B3 in Cancer Cell Lines

[1] Giacomini KM(2010)Membrane transporters in drug development Nat Rev Drug Discov 9 215-236

[2] Huang SM(2008)Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family Xenobiotica 38 778-801

[3] Tweedie DJ(2008)Impact of genetic polymorphisms of transporters on the pharmacokinetic, pharmacodynamic and toxicological properties of anionic drugs Drug Metab Pharmacokinet 23 223-235

[4] Benet LZ(2012)Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver J Clin Invest 122 519-528

[5] Brouwer KL(2001)LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers Gastroenterology 120 1689-1699

[6] Chu X(2007)Human liver-specific organic anion transporter-2 is a potent prognostic factor for human breast carcinoma Cancer Sci 98 1570-1576

[7] Hagenbuch B(2007)Potent cytotoxicity of the phosphatase inhibitor microcystin LR and microcystin analogues in OATP1B1- and OATP1B3-expressing HeLa cells Mol Cancer Ther 6 587-598

[8] Gui C(2008)Overexpression of OATP1B3 confers apoptotic resistance in colon cancer Cancer Res 68 10315-10323

[9] Maeda K(2008)Effect of SLCO1B3 haplotype on testosterone transport and clinical outcome in caucasian patients with androgen-independent prostatic cancer Clin Cancer Res 14 3312-3318

[10] Sugiyama Y(2011)Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport Biomed Pharmacother 65 417-426

[1] Giacomini KM(2010)Membrane transporters in drug development Nat Rev Drug Discov 9 215-236

[2] Huang SM(2008)Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family Xenobiotica 38 778-801

[3] Tweedie DJ(2008)Impact of genetic polymorphisms of transporters on the pharmacokinetic, pharmacodynamic and toxicological properties of anionic drugs Drug Metab Pharmacokinet 23 223-235

[4] Benet LZ(2012)Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver J Clin Invest 122 519-528

[5] Brouwer KL(2001)LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers Gastroenterology 120 1689-1699

[6] Chu X(2007)Human liver-specific organic anion transporter-2 is a potent prognostic factor for human breast carcinoma Cancer Sci 98 1570-1576

[7] Hagenbuch B(2007)Potent cytotoxicity of the phosphatase inhibitor microcystin LR and microcystin analogues in OATP1B1- and OATP1B3-expressing HeLa cells Mol Cancer Ther 6 587-598

[8] Gui C(2008)Overexpression of OATP1B3 confers apoptotic resistance in colon cancer Cancer Res 68 10315-10323

[9] Maeda K(2008)Effect of SLCO1B3 haplotype on testosterone transport and clinical outcome in caucasian patients with androgen-independent prostatic cancer Clin Cancer Res 14 3312-3318

[10] Sugiyama Y(2011)Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport Biomed Pharmacother 65 417-426