Monitoring for Extra-Intestinal Cancers in IBD

被引:12
作者
Sifuentes H. [1 ]
Kane S. [2 ]
机构
[1] Department of Gastroenterology and Hepatology, Georgia Regents University, 1120 15th Street, AD 2226, Augusta, 30912, GA
[2] Department of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, 55905, MN
关键词
Cervical cancer; Cervical dysplasia; Crohn’s disease; Extra-intestinal cancers; Hepatosplenic T cell lymphoma; Inflammatory bowel disease; Lymphoma; Lymphoproliferative disorders; Melanoma; Non-Hodgkin lymphoma; Non-melanoma skin cancer; Ulcerative colitis;
D O I
10.1007/s11894-015-0467-8
中图分类号
学科分类号
摘要
Multiple studies have demonstrated an increased risk for extra-intestinal cancers in inflammatory bowel disease (IBD) patients, mainly from treatment modalities. Prominent cancers that are related to IBD treatment include the following: lymphoproliferative disorders associated with thiopurine use, hepatosplenic T cell lymphoma primarily in younger male patients on thiopurines and anti-tumor necrosis factor (TNF) agents, non-melanoma skin cancers in patients treated with thiopurines and anti-TNF agents, and melanomas in patients who are on monotherapy with anti-TNF agents. In addition, women with IBD may have higher rates of cervical dysplasia and cervical cancer. The focus of this review is to provide a comprehensive overview on extra-intestinal cancers in IBD patients and how to monitor for these malignancies. © 2015, Springer Science+Business Media New York.
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页数:5
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