Reproducibility of scanning laser polarimetry (GDx) of peripapillary retinal nerve fiber layer thickness in normal subjects

被引:0
作者
Kook M.S. [1 ]
Sung K. [1 ]
Park R.-H. [1 ]
Kim K.-R. [1 ]
Kim S.-T. [1 ]
Kang W. [2 ]
机构
[1] Department of Ophthalmology, Ulsan University School of Medicine, Asan Medical Center, Seoul 138-736, 388-1 Pungnap-dong, Songpa-gu
[2] Consulting Unit for Biostatistics, Ulsan University School of Medicine, Asan Medical Center
关键词
Layer Thickness; Scanning Laser; Retinal Nerve Fiber Layer; Retinal Nerve Fiber Layer Thickness; Consecutive Time;
D O I
10.1007/s004170000247
中图分类号
学科分类号
摘要
Purpose: To assess the reproducibility of measurement of retinal nerve fiber layer (RNFL) thickness among subjects using the GDx Nerve Fiber Analyzer (NFA). Methods: One eye of each of five young and healthy volunteers was imaged by three newly trained technicians (R.-H.P, K.-R.K., and S.-T.K.). Each volunteer was scanned six consecutive times for five independent-times within a 1-month period. One composite image was selected out of three best images per session. Intra- and inter-operator reproducibilities were calculated and the influence of placement of measurement ellipse by a single operator on interobserver reproducibility was also investigated. Results: Mean coefficients of variation for total integral value of RNFL were 3.67±1.47%, 3.86±2.13%, and 4.16±1.97%, respectively for the three technicians. Interoperator variability was not statistically significant (P=0.075), and the difference was even less if a single ellipse drawn by one operator was used in all measurements (P=0.1528) by repeated-measures analysis of variance (ANOVA). Conclusions: The results suggest that GDx NFA may provide acceptable intraoperator as well as interoperator reproducibility among Asian eyes.
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页码:118 / 121
页数:3
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