The Transepithelial Transport of a G-CSF-Transferrin Conjugate in Caco-2 Cells and Its Myelopoietic Effect in BDF1 Mice

被引：0
|
作者：
Adam Widera
Yun Bai
Wei-Chiang Shen
机构：
[1] University of Southern California,Department of Pharmaceutical Sciences, School of Pharmacy
来源：
Pharmaceutical Research | 2004年 / 21卷
关键词：
Caco-2; G-CSF-Tf; oral protein-drug delivery; transepithelial transport.;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. The purpose of this study was to investigate the transferrin-receptor (TfR)-mediated transepithelial transport of G-CSF-transferrin (Tf) conjugate in cultured enterocyte-like Caco-2 monolayers and the myelopoietic effect of subcutaneously and orally administered G-CSF-Tf in BDF1 mice.
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页码：278 / 284
页数：6
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