Interaction of the novel antipsychotic aripiprazole with 5-HT1A and 5-HT2A receptors: functional receptor-binding and in vivo electrophysiological studies

Andrade R(1998)Regulation of membrane excitability in the central nervous system by serotonin receptor subtypes Ann N Y Acad Sci 861 190-203

Bardin L(2005)Antipsychotic-like vs cataleptogenic actions in mice of novel antipsychotics having D(2) antagonist and 5-HT(1A) agonist properties Neuropsychopharmacology 31 1869-1879

Kleven MS(1987)Modification of 5-HT neuron properties by sustained administration of the 5-HT1A agonist gepirone: electrophysiological studies in the rat brain Synapse 1 470-480

Barret-Grevoz C(1976)A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein–dye binding Anal Biochem 72 248-254

Depoortere R(2002)Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptors J Pharmacol Exp Ther 302 381-389

Newman-Tancredi A(1994)The inhibitory effect of 8-OH-DPAT on the firing activity of dorsal raphe serotoninergic neurons in rats is attenuated by lesion of the frontal cortex Neuropharmacology 33 709-713

Blier P(1973)Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction Biochem Pharmacol 22 3099-3108

de Montigny C(2005)Clozapine, ziprasidone and aripiprazole but not haloperidol protect against kainic acid-induced lesion of the striatum in mice, in vivo: role of 5-HT Brain Res 1043 32-41

Bradford MM(2004) receptor activation CNS Drug Rev 10 317-336

Burris KD(1999)Aripiprazole: a novel atypical antipsychotic drug with a uniquely robust pharmacology Br J Pharmacol 126 1741-1750

Andrade R(1998)Regulation of membrane excitability in the central nervous system by serotonin receptor subtypes Ann N Y Acad Sci 861 190-203

Bardin L(2005)Antipsychotic-like vs cataleptogenic actions in mice of novel antipsychotics having D(2) antagonist and 5-HT(1A) agonist properties Neuropsychopharmacology 31 1869-1879

Kleven MS(1987)Modification of 5-HT neuron properties by sustained administration of the 5-HT1A agonist gepirone: electrophysiological studies in the rat brain Synapse 1 470-480

Barret-Grevoz C(1976)A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein–dye binding Anal Biochem 72 248-254

Depoortere R(2002)Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptors J Pharmacol Exp Ther 302 381-389

Newman-Tancredi A(1994)The inhibitory effect of 8-OH-DPAT on the firing activity of dorsal raphe serotoninergic neurons in rats is attenuated by lesion of the frontal cortex Neuropharmacology 33 709-713

Blier P(1973)Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction Biochem Pharmacol 22 3099-3108

de Montigny C(2005)Clozapine, ziprasidone and aripiprazole but not haloperidol protect against kainic acid-induced lesion of the striatum in mice, in vivo: role of 5-HT Brain Res 1043 32-41

Bradford MM(2004) receptor activation CNS Drug Rev 10 317-336

Burris KD(1999)Aripiprazole: a novel atypical antipsychotic drug with a uniquely robust pharmacology Br J Pharmacol 126 1741-1750