The current role of MRI in differentiating multiple sclerosis from its imaging mimics (vol 14, pg 199, 2018)

被引：40

作者：

Geraldes, Ruth

Ciccarelli, Olga

Barkhof, Frederik

De Stefano, Nicola

Enzinger, Christian

Filippi, Massimo

Hofer, Monika

Paul, Friedemann

Preziosa, Paolo

Rovira, Alex

DeLuca, Gabriele C.

Kappos, Ludwig

Yousry, Tarek

Fazekas, Franz

Frederiksen, Jette

Gasperini, Claudio

Sastre-Garriga, Jaume

Evangelou, Nikos

Palace, Jacqueline

机构：

[1] Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford

[2] University College London, London

[3] National Institute for Health Research, University College London Hospitals Biomedical Research Centre, London

[4] Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam

[5] Neurology and Neurometabolic Unit, Department of Neurological and Behavioural Sciences, University of Siena, Siena

[6] Department of Neurology, Medical University of Graz, Graz

[7] Division of Neuroradiology, Vascular and Interventional Radiology, Medical University of Graz, Graz

[8] Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan

[9] Neuropathology Department, John Radcliffe Hospital, Oxford

[10] NeuroCure Clinical Research Center and Experimental, Clinical Research Center, Max Delbrück Center for Molecular Medicine, Charité - Universitätsmedizin Berlin, Berlin

[11] Magnetic Resonance Unit, Department of Radiology, Hospital Universitari Vall d'Hebron, Universitat Autonoma de Barcelona, Barcelona

[12] Department of Neurology, University Hospital Basel, Basel

[13] Institute of Neurology, Queen Square, London

[14] Department of Neurology, Rigshospitalet Glostrup, University of Copenhagen, Copenhagen

[15] Multiple Sclerosis Centre, Department of Neurosciences, San Camillo-Forlanini Hospital, Rome

[16] Centre d'Esclerosi Multiple de Catalunya (Cemcat), Department of Neurology/Neuroimmunology, Hospital Universitari Vall d'Hebron, Universitat Autonoma de Barcelona, Barcelona

[17] Division of Neurosciences, School of Medicine, University of Nottingham, Queen's Medical Centre Campus, Nottingham

来源：

NATURE REVIEWS NEUROLOGY | 2018年 / 14卷 / 04期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1038/nrneurol.2018.39

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

MRI red flags proposed over a decade ago by the European Magnetic Resonance Network in MS (MAGNIMS) have guided clinicians in the diagnosis of multiple sclerosis (MS). However, the past 10 years have seen increased recognition that vascular disease can coexist and possibly interact with MS, improvements in the reliability of ways to differentiate MS from novel antibody-mediated CNS disorders (such as anti-aquaporin-4 antibody and myelin-oligodendrocyte glycoprotein antibody-associated diseases) and advances in MRI techniques. In this Review, MAGNIMS updates the imaging features that differentiate the most common mimics of MS, particularly age-related cerebrovascular disease and neuromyelitis optica, from MS itself. We also provide a pragmatic summary of the clinically useful MRI features that distinguish MS from its mimics and discuss the future of nonconventional techniques that have identified promising disease-specific features.

引用

页码：213 / 213

页数：1