A bispecific diabody directed against prostate-specific membrane antigen and CD3 induces T-cell mediated lysis of prostate cancer cells

被引:0
作者
P. Bühler
P. Wolf
D. Gierschner
I. Schaber
A. Katzenwadel
W. Schultze-Seemann
U. Wetterauer
M. Tacke
M. Swamy
W. W. A. Schamel
U. Elsässer-Beile
机构
[1] University of Freiburg,Department of Urology, Experimental Urology
[2] University of Freiburg,Faculty of Biology
[3] University of Freiburg,Institute of Molecular Medicine and Cell Research
[4] Max-Planck-Institute for Immunobiology and University of Freiburg,Department of Molecular Immunology
来源
Cancer Immunology, Immunotherapy | 2008年 / 57卷
关键词
PSMAxCD3 bispecific diabody; Prostate cancer; T-cell targeting; Immunotherapy;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:43 / 52
页数:9
相关论文
共 215 条
[31]  
Kipriyanov SM(1995)Bispecific monoclonal antibody therapy of B-cell malignancy Leuk Lymphoma 16 199-195
[32]  
Stassar MJ(1994)Target cell induced T-cell activation with bispecific antibodies: a new concept for tumor immunotherapy Recent Results Cancer Res 135 185-1373
[33]  
Christ O(2006)A recombinant PSMA-specific single-chain immunotoxin has potent and selective toxicity against prostate cancer cells Cancer Immunol Immunother 55 1367-36
[34]  
Schuhmacher J(1996)Tumor localization of anti-CEA single-chain Fvs: improved targeting by non-covalent dimers Immunotechnology 2 21-undefined
[35]  
Strauss G(undefined)undefined undefined undefined undefined-undefined
[36]  
Moldenhauer G(undefined)undefined undefined undefined undefined-undefined
[37]  
Little M(undefined)undefined undefined undefined undefined-undefined
[38]  
Dreier T(undefined)undefined undefined undefined undefined-undefined
[39]  
Baeuerle PA(undefined)undefined undefined undefined undefined-undefined
[40]  
Fichtner I(undefined)undefined undefined undefined undefined-undefined