Targeted modulation of immune cells and tissues using engineered biomaterials

被引：62

作者：

Yousefpour, Parisa ^{[1
]}

Ni, Kaiyuan ^{[1
]}

Irvine, Darrell J. ^{[1
,2
,3
,4
,5
,6
]}

机构：

[1] MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA

[2] MIT, Dept Biol Engn, Cambridge, MA 02139 USA

[3] MIT, Dept Mat Sci & Engn, Cambridge, MA 02139 USA

[4] MIT, Ragon Inst Massachusetts Gen Hosp, Cambridge, MA 02139 USA

[5] Harvard Univ, Cambridge, MA 02138 USA

[6] Howard Hughes Med Inst, Chevy Chase, MD 20815 USA

来源：

NATURE REVIEWS BIOENGINEERING | 2023年 / 1卷 / 02期

关键词：

CD8(+) T-CELLS; NEUTRALIZING ANTIBODY-RESPONSES; ANTIGEN-PRESENTING CELLS; DENDRITIC CELLS; SOLID TUMORS; IN-VIVO; VASCULAR NORMALIZATION; NANOPARTICLE VACCINES; 1ST-IN-HUMAN PHASE-1; TRAINED IMMUNITY;

D O I：

10.1038/s44222-022-00016-2

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Therapies modulating the immune system offer the prospect of treating a wide range of conditions including infectious diseases, cancer and autoimmunity. Biomaterials can promote specific targeting of immune cell subsets in peripheral or lymphoid tissues and modulate the dosage, timing and location of stimulation, thereby improving the safety and efficacy of vaccines and immunotherapies. Here, we review recent advances in biomaterials-based strategies, focusing on targeting of lymphoid tissues, circulating leukocytes, tissue-resident immune cells and immune cells at disease sites. These approaches can improve the potency and efficacy of immunotherapies by promoting immunity or tolerance against different diseases.

引用

页码：107 / 124

页数：18

共 50 条

[41] Endothelial Progenitor Cells for the Vascularization of Engineered Tissues
Peters, Erica B.
TISSUE ENGINEERING PART B-REVIEWS, 2018, 24 (01) : 1 - 24
[42] Immune cells targeted in cancer
Nature, 2014, 510 (7504) : 191 - 191
[43] Interactions between Biomaterials and Biological Tissues and Cells, Part I
Du, Jing
Katti, Dinesh
Thomas, Vinoy
JOM, 2022, 74 (09) : 3334 - 3335
[44] Interactions between Biomaterials and Biological Tissues and Cells, Part I
Jing Du
Dinesh Katti
Vinoy Thomas
JOM, 2022, 74 : 3334 - 3335
[45] Recent Advances in Biomaterials for mRNA Delivery to Immune Cells
Isaac, Ivan
Bhatia, Mayurakkhi
Bhattacharya, Chandrabali
ACS APPLIED BIO MATERIALS, 2024, 7 (08): : 5136 - 5146
[46] Minireview: biocompatibility of engineered biomaterials, their interaction with the host cells, and evaluation of their properties
Jimenez-Rosales, Angelica
Cortes-Camargo, Stefani
Estanislao Acuna-Avila, Pedro
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, 2024, 73 (01) : 45 - 60
[47] Microenvironmental Modulation of Calcium Wave Propagation Velocity in Engineered Cardiac Tissues
Andrew P. Petersen
Davi M. Lyra-Leite
Nethika R. Ariyasinghe
Nathan Cho
Celeste M. Goodwin
Joon Young Kim
Megan L. McCain
Cellular and Molecular Bioengineering, 2018, 11 : 337 - 352
[48] Microenvironmental Modulation of Calcium Wave Propagation Velocity in Engineered Cardiac Tissues
Petersen, Andrew P.
Lyra-Leite, Davi M.
Ariyasinghe, Nethika R.
Cho, Nathan
Goodwin, Celeste M.
Kim, Joon Young
McCain, Megan L.
CELLULAR AND MOLECULAR BIOENGINEERING, 2018, 11 (05) : 337 - 352
[49] Tissue-Engineered Cartilage: The Crossroads of Biomaterials, Cells and Stimulating Factors
Bhardwaj, Nandana
Devi, Dipali
Mandal, Biman B.
MACROMOLECULAR BIOSCIENCE, 2015, 15 (02) : 153 - 182
[50] Evaluation of the interaction between epithelial and stromal mammary cells using engineered breast tissues
Rouabhia, M
Grimard, Y
Coté-Richer, M
Jacob, S
Deschines, L
FASEB JOURNAL, 1999, 13 (04): : A256 - A256

← 1 2 3 4 5 →