Synthesis of halogenated derivatives of thymol and their antimicrobial activities

被引：0

作者：

Ranjeet Kaur

Mahendra P. Darokar

Sunil Kumar Chattopadhyay

Vinay Krishna

Ateeque Ahmad

机构：

[1] Central Institute of Medicinal and Aromatic Plants (CSIR),Process Chemistry and Chemical Engineering Department

[2] Central Institute of Medicinal and Aromatic Plants (CSIR),Genetic Resource Biotechnology Department

来源：

Medicinal Chemistry Research | 2014年 / 23卷

关键词：

Thymol derivatives; -Halosuccinimide; Antibacterial activity; Antifungal activity;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

In order to test the antibacterial and antifungal activities of different halogenated thymol derivatives, thymol has been converted into chlorothymol, dichlorothymol with N-chlorosuccinimide; monobromothymol, dibromothymol with N-bromosuccinimide; O-methylated iodothymol with ceric ammonium nitrate and iodine from methylated thymol. Among the different derivatives tested, 4-chlorothymol was found to be most active against Staphylococcus aureus and Staphylococcusepidermis at a concentration of 12.5 and 25 ppm, respectively. Also it was tested to be active against Candida albicans (AI).

引用

页码：2212 / 2217

页数：5

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