Posterior fossa abnormalities seen on magnetic resonance brain imaging in a cohort of newborn infants

被引：35
作者：
Lawrence S Miall
Luc G Cornette
Steven F Tanner
Rosemary J Arthur
Malcolm I Levene
机构：
[1] Dept. of Paediatrics/Child Health, University of Leeds, Leeds
[2] Academic Unit of Medical Physics, University of Leeds, Leeds
[3] Department of Paediatric Radiology, The Leeds Teaching Hosp. NHS Trust, Leeds
来源：
Journal of Perinatology | 2003年 / 23卷 / 5期
关键词：
D O I：
10.1038/sj.jp.7210941
中图分类号：
学科分类号：
摘要：
Objective: To describe the nature and frequency of posterior fossa (PF) lesions in infants who underwent magnetic resonance (MR) brain imaging in the neonatal period and to correlate with cranial ultrasound (CUS) findings and clinical outcome. Study Design: A retrospective review of all neonatal MR brain imaging from 1996 to 2001 (n = 558). MR images, CUS and case notes were reviewed in infants with PF abnormality. Results: A total of 20 infants had abnormalities in the PF, which represents 4.7% of abnormalities seen on MR. Out of 10, six term infants had PF extraaxial hemorrhage, three had cerebellar hypoplasia, while one had cerebellar hemorrhage. In the preterm, 8/10 lesions were unilateral; focal cerebellar hemorrhage was seen 5/10 and extensive hemorrhage with secondary atrophy in 3/10. Out of 20, 17 infants also had supratentorial lesions. Out of 20, 19 had CUS performed, of which 7/19 showed PF abnormality. Conclusion: Intracerebellar hemorrhage was more common in preterm infants than in term infants. These hemorrhages tended to be focal, unilateral and were associated with atrophy.
引用
收藏
页码：396 / 403
页数：7
相关论文
共 23 条
  • [1] Merrill J.D., Piecuch R.E., Fell S.C., Barkovich A.J., Goldstein R.B., A new pattern of cerebellar hemorrhages in preterm infants, Pediatrics, 102, (1998)
  • [2] Luna J.A., Goldstein R.B., Sonographic visualization of neonatal posterior fossa abnormalities through the posterolateral fontanelle, AJR, 174, pp. 561-567, (2000)
  • [3] Martin R., Roessmann U., Fanaroff A., Massive intracerebellar hemorrhage in low-birth-weight infants, J. Pediatr., 89, pp. 290-293, (1976)
  • [4] Grunnet M.L., Shields W.D., Cerebellar hemorrhage in the premature infant, J. Pediatr., 88, pp. 605-608, (1976)
  • [5] Pape K.E., Armstrong D.L., Fitzhardinge P.M., Central nervous system pathology associated with mask ventilation in the very low birthweight infant: A new etiology for intracerebellar hemorrhages, Pediatrics, 58, pp. 473-483, (1976)
  • [6] Rutherford M.A., Haemorrhagic lesions of the newborn brain, MRI of the Neonatal Brain, pp. 171-200, (2001)
  • [7] Mercuri E., He J., Curati W.L., Dubowitz L.M., Cowan F.M., Bydder G.M., Cerebellar infarction and atrophy in infants and children with a history of premature birth, Pediatr. Radiol., 27, pp. 139-143, (1997)
  • [8] Tuck S., Ment L.R., A follow-up study of very low-birthweight infants receiving ventilatory support by face mask, Dev. Med. Child Neurol., 22, pp. 633-641, (1980)
  • [9] Huang L.T., Lui C.C., Tentorial hemorrhage associated with vacuum extraction in a newborn, Pediatr. Radiol., 25, SUPPL. 1, (1995)
  • [10] Bulas D.I., Taylor G.A., Fitz C.R., Revenis M.E., Glass P., Ingram J.D., Posterior fossa intracranial hemorrhage in infants treated with extracorporeal membrane oxygenation: Sonographic findings, AJR AM. J. Roenterol., 156, 3, pp. 571-575, (1991)
123