New Approaches to Nanotheranostics: Polyfunctional Magnetic Nanoparticles Activated by Non-Heating Low-Frequency Magnetic Field Control Biochemical System with Molecular Locality and Selectivity

被引：18

作者：

Golovin Y.I. ^{[1
,2
,3
]}

Klyachko N.L. ^{[1
,5
]}

Majouga A.G. ^{[1
,3
,4
]}

Gribanovskii S.L. ^{[2
]}

Golovin D.Y. ^{[2
]}

Zhigachev A.O. ^{[2
]}

Shuklinov A.V. ^{[2
]}

Efremova M.V. ^{[1
,3
]}

Veselov M.M. ^{[1
]}

Vlasova K.Y. ^{[1
]}

Usvaliev A.D. ^{[1
]}

Le-Deygen I.M. ^{[1
]}

Kabanov A.V. ^{[1
,5
]}

机构：

[1] Lomonosov Moscow State University, Moscow

[2] Derzhavin Tambov State University, Tambov

[3] National University of Science and Technology MISiS, Moscow

[4] Mendeleev University of Chemical Technology of Russia, Moscow

[5] University of North Carolina at Chapel Hill, Chapel Hill, 27599, NC

来源：

Nanotechnologies in Russia | 2018年 / 13卷 / 5-6期

基金：

俄罗斯基础研究基金会; 俄罗斯科学基金会;

关键词：

Nanomagnetics - Magnetic fields - Nanoparticles - Biochemistry;

D O I：

10.1134/S1995078018030060

中图分类号：

学科分类号：

摘要：

In this work, a novel approach to magnetic nanotheranostics based on the activation of magnetic nanoparticles (MNPs) with a nonheating low-frequency magnetic field has been described. Electromagnetic biomedical technologies implemented in low-frequency nonheating and radiofrequency heating magnetic fields have been briefly reviewed and compared. It has been shown that the activation of MNPs with nonheating magnetic fields has several advantages over activation with heating magnetic fields, namely, a more universal character and penetration ability into tissues, easy dosage and control, higher locality and safety, molecular selectivity, and lower cost. A combination of methods developed and patented by us can form a technological platform for new-generation low-frequency magnetic theranostics which is significantly more effective and possesses more options than conventional radiofrequency theranostics. © 2018, Pleiades Publishing, Ltd.

引用

页码：215 / 239

页数：24

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