Some Structural Aspects of the Peptidyl Transferase Reaction

[1] Lim V.I.(1986)Stereochemical analysis of ribosomal transpeptidation. Conformation of nascent peptide J. Mol. Biol. 188 565-577

[2] Spirin A.S.(2000)The complete atomic structure of the large riboso-mal subunit at 2.4 Å resolution Science 289 905-920

[3] Ban N.(2001)High-resolution structure of the large ribosomal subunit from a mesophillic eubacterium Cell 107 679-688

[4] Nissen P.(2000)The structural basis of ribosome activity in peptide bond formation Science 289 920-930

[5] Hansen J.(2001)Ribosomal peptidyltransferase can withstand mutations at the putative catalytic nucleotide Nature 411 498-501

[6] Moore P.B.(2001)pKa of adenine 2451 in the ribosomal peptidyl transferase center remains elusive RNA 7 1365-1369

[7] Steitz T.A.(2001)Mechanism of peptide bond formation Science 291 203-10101

[8] Harms J.(2001)A conformational change in the riboso-mal peptidyl transferase center upon active / inactive transition Proc. Natl. Acad. Sci. USA 98 10096-230

[9] Schluenzen F.(2002)A pre-translocation intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits Nature Struct. Biol. 9 225-11675

[10] Zarivach R.(2002)Structural insights into peptide bond formation Proc. Natl. Acad. Sci. USA 99 11670-102

[1] Lim V.I.(1986)Stereochemical analysis of ribosomal transpeptidation. Conformation of nascent peptide J. Mol. Biol. 188 565-577

[2] Spirin A.S.(2000)The complete atomic structure of the large riboso-mal subunit at 2.4 Å resolution Science 289 905-920

[3] Ban N.(2001)High-resolution structure of the large ribosomal subunit from a mesophillic eubacterium Cell 107 679-688

[4] Nissen P.(2000)The structural basis of ribosome activity in peptide bond formation Science 289 920-930

[5] Hansen J.(2001)Ribosomal peptidyltransferase can withstand mutations at the putative catalytic nucleotide Nature 411 498-501

[6] Moore P.B.(2001)pKa of adenine 2451 in the ribosomal peptidyl transferase center remains elusive RNA 7 1365-1369

[7] Steitz T.A.(2001)Mechanism of peptide bond formation Science 291 203-10101

[8] Harms J.(2001)A conformational change in the riboso-mal peptidyl transferase center upon active / inactive transition Proc. Natl. Acad. Sci. USA 98 10096-230

[9] Schluenzen F.(2002)A pre-translocation intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits Nature Struct. Biol. 9 225-11675

[10] Zarivach R.(2002)Structural insights into peptide bond formation Proc. Natl. Acad. Sci. USA 99 11670-102