Exposure to Cats: Update on Risks for Sensitization and Allergic Diseases

被引:32
作者
Dharmage, Shyamali C. [1 ,2 ,3 ]
Lodge, Caroline L. [2 ]
Matheson, Melanie C. [2 ]
Campbell, Brittany [2 ]
Lowe, Adrian J. [2 ,3 ]
机构
[1] Univ Melbourne, Ctr Mol Environm Genet & Analyt Epidemiol, Sch Populat Hlth Dent & Hlth Sci, Carlton, Vic 3053, Australia
[2] Univ Melbourne, Ctr Mol Environm Genet & Analyt MEGA Epidemiol, Melbourne Sch Populat Hlth, Melbourne, Vic, Australia
[3] Royal Childrens Hosp, Murdoch Childrens Res Inst, Melbourne, Vic, Australia
基金
英国医学研究理事会;
关键词
Cat exposure; Cat allergens; Fel d 1; Asthma; Eczema; Atopic dermatitis; Allergic; Review; Rhinitis; Conjunctivitis; Sensitization; Allergies; Pets; Cats; Risks; HOUSE-DUST-MITE; MELBOURNE SCHOOLCHILDREN; INDOOR ALLERGENS; CHILDHOOD PETS; BIRTH COHORT; FURRY PETS; HAY-FEVER; ASTHMA; DOG; PREVALENCE;
D O I
10.1007/s11882-012-0288-x
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Cats are the pets most commonly implicated in the etiology of asthma and allergic disease. However, systematic reviews have concluded that there is a lack of evidence to support the idea that cat exposure in early life increases the risk of allergic disease. Indeed, it appears most likely that cat exposure is protective against allergic diseases. Recent large prospective studies have shown that living with a cat during childhood, especially during the first year of a child's life, could be protective. However, any advice given to the parents should also incorporate how new acquisition of cats can affect other family members, especially those who are already sensitized. Research is urgently needed to determine whether the suggested impact of acquisition of cats in adult life is modified by the person's childhood pet ownership, to help parents who seek advice on whether or not to get a cat.
引用
收藏
页码:413 / 423
页数:11
相关论文
共 71 条
  • [1] Abbing-Karahagopian V, 2012, PEDIAT ALLERGY IMMUN
  • [2] NORDPET -: Pets indoors -: A risk factor for or protection against sensitisation/allergy -: A Nordic interdisciplinary review of the scientific literature concerning the relationship between the exposure to pets at home, sensitisation and the development of allergy
    Ahlbom, A
    Backman, A
    Bakke, J
    Foucard, T
    Halken, S
    Kjellman, NIM
    Malm, L
    Skerfving, S
    Sundell, J
    Zetterström, O
    [J]. INDOOR AIR, 1998, 8 (04) : 219 - 235
  • [3] Systematic review: Exposure to pets and risk of asthma and asthma-like symptoms
    Apelberg, BJ
    Aoki, Y
    Jaakkola, JJK
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2001, 107 (03) : 455 - 460
  • [4] Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood:: ISAAC Phases One and Three repeat multicountry cross-sectional surveys
    Asher, M. Innes
    Montefort, Stephen
    Bjorksten, Bengt
    Lai, Christopher K. W.
    Strachan, David P.
    Weiland, Stephan K.
    Williams, Hywel
    [J]. LANCET, 2006, 368 (9537) : 733 - 743
  • [5] Domestic aeroallergen exposures among infants in an English town
    Atkinson, W
    Harris, J
    Mills, P
    Moffat, S
    White, C
    Lynch, O
    Jones, M
    Cullinan, P
    Taylor, AJN
    [J]. EUROPEAN RESPIRATORY JOURNAL, 1999, 13 (03) : 583 - 589
  • [6] Bateman BJ, 1999, CLIN EXP ALLERGY, V29, P725
  • [7] Bianca AD, 2012, J TROPICAL PEDIAT
  • [8] Gene-environment interaction in the onset of eczema in infancy: Filaggrin loss-of-function mutations enhanced by neonatal cat exposure
    Bisgaard, Hans
    Simpson, Angela
    Palmer, Colin N. A.
    Bonnelykke, Klaus
    Mclean, Irwin
    Mukhopadhyay, Somnath
    Pipper, Christian B.
    Halkjaer, Liselotte B.
    Lipworth, Brian
    Hankinson, Jenny
    Woodcock, Ashley
    Custovic, Adnan
    [J]. PLOS MEDICINE, 2008, 5 (06): : 0934 - 0940
  • [9] Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 Revision
    Brozek, Jan L.
    Bousquet, Jean
    Baena-Cagnani, Carlos E.
    Bonini, Sergio
    Canonica, G. Walter
    Casale, Thomas B.
    van Wijk, Roy Gerth
    Ohta, Ken
    Zuberbier, Torsten
    Schuenemann, Holger J.
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2010, 126 (03) : 466 - 476
  • [10] Fungal DNA, allergens, mycotoxins and associations with asthmatic symptoms among pupils in schools from Johor Bahru, Malaysia
    Cai, Gui-Hong
    Hashim, Jamal Hisham
    Hashim, Zailina
    Ali, Faridah
    Bloom, Erica
    Larsson, Lennart
    Lampa, Erik
    Norback, Dan
    [J]. PEDIATRIC ALLERGY AND IMMUNOLOGY, 2011, 22 (03) : 290 - 297