Role of Radical Prostatectomy in Clinically Non-Organ-Confined Prostate Cancer

被引：0
作者：
Christian Gratzke
Jutta Engel
Christian G. Stief
机构：
[1] Ludwig-Maximilians-University Munich,Department of Urology
[2] Munich Cancer Registry,undefined
来源：
Current Urology Reports | 2014年 / 15卷
关键词：
Radical prostatectomy; Prostate cancer; Metastasis; Lymph node; Survival;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In patients with lymph node-positive and metastatic prostate cancer there is currently no consensus about the best possible management. Multimodal approaches including systemic and local treatment have shown to improve survival. However, the role of radical prostatectomy (RP) is currently unclear. While treatment of the primary tumor is recommended in highly selected lymph node-positive prostate cancer patients, no prospective data exist to support resection of the primary tumor in metastatic patients as a treatment modality to improve overall survival. However, recent observational studies have suggested a survival benefit after prostate tumor cytoreduction. This article reviews existing evidence on the role of RP in lymph node-positive and metastatic prostate cancer patients.
引用
收藏
相关论文
共 83 条
  • [11] Mitin T(2014)No improvement noted in overall or cause-specific survival for men presenting with metastatic prostate cancer over a 20-year period Cancer 120 818-23
  • [12] Blute M(2007)Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the management of peritoneal surface malignancies of colonic origin: a consensus statement. Society of surgical oncology Ann Surg Oncol 14 128-33
  • [13] Lee R(2012)Role of cytoreductive nephrectomy in the era of targeted therapy for renal cell carcinoma Curr Urol Rep 13 38-46
  • [14] Efstathiou J(2014)Cytoreductive surgery for advanced ovarian cancer Women’s Health (Lond Engl) 10 179-90
  • [15] Engel J(2013)Re: Stephen H. Culp, Paul F. Schellhammer, Michael B. Williams. Might men diagnosed with metastatic prostate cancer benefit from definitive treatment of the primary tumor? A seer-based study Eur Urol 89 16-26
  • [16] Bastian PJ(2014)Re: Stephen H. Culp, Paul F. Schellhammer, Michael B. Williams. Might men diagnosed with metastatic prostate cancer benefit from definitive treatment of the primary tumor? A seer-based study Eur Urol 65 693-700
  • [17] Baur H(2014)Surgery, wound healing, and metastasis: recent insights and clinical implications Crit Rev Oncol Hematol undefined undefined-undefined
  • [18] Beer V(2014)Cancer-specific survival after metastasis following primary radical prostatectomy compared with radiation therapy in prostate cancer patients: results of a population-based, propensity score-matched analysis Eur Urol undefined undefined-undefined
  • [19] Chaussy C(undefined)undefined undefined undefined undefined-undefined
  • [20] Gschwend JE(undefined)undefined undefined undefined undefined-undefined
123456789